ABSTRACT
Functional mitral regurgitation [FMR] results from left ventricular remodeling, anterior leaflet tethering or tenting. Coronary artery disease is one of the important causes of FMR due to tethering. Detection of FMR and its severity is one of important factors in patient prognosis. There are different methods for detection of FMR and its severity, including anterior mitral leaflet concavity area [AMLCA]. In this cross sectional study 32 patients were selected, 19 of them were male with three vessel disease [3VD] and were candidate for coronary bypass graft surgery [CABG] with or without mitral valve surgery. They had FMR in ventriculography. Anterior mitral leaflet concavity area [AMLCA] was determined by long axis view [LAX] of transthorasic echocardiography [TTE]. Relation between severity of MR and AMLCA determined with Spearman's correlation coefficient and according to Roc curve study cut-off point was 0.1 cm[2]. Statistical analysis was performed using SPSS Version 15. In studied patients, AMLCA were 0.1-0.43 cm[2] in transthorasic echocardiography [cutoff point was 0.1 cm[2]]. A strong correlation was seen between AMLCA and FMR severity with LAX view of TTE [r=0.89]. Relation between FMR and AMLCA was a simple linear relationship. The results showed that AMILCA in the parasternal LAX view provides rapid and reliable diagnosis of FMR due to coronary artery disease and is quantitatively related to the severity of MR. In this regard, further studies with more subjects are recommended