Meconium-stained amniotic fluid as a risk factor for perinatal asphyxia

Background: The aim of this study was to find out immediate fetal outcome in meconium-stained amniotic fluid in relation to perinatal asphyxia.Methods: This retrospective study includes medical records of all neonates admitted to Neonatal Intensive Care Unit (NICU) between December 2016 and July 2018. The variables reviewed are age, sex, weight, mode of delivery, gestational age, presence of meconium aspiration syndrome (MAS) and perinatal asphyxia.Results: Out of 408 total admissions in NICU, 69.1% were male babies and remaining 30.9% were female babies. In the study out of 36 subjects with Perinatal Asphyxia, 38.9% had MAS and 61.1% had not MAS. Out of 372 subjects without perinatal asphyxia, 93.8% had no MAS and 6.2% had MAS. There was significant association between MAS and perinatal asphyxia. Odds ratio was 9.656. i.e. those with MAS had 9.656 times higher risk for perinatal asphyxia.Conclusions: The management of MAS, which is a perinatal problem, requires a well concerted and coordinated action by the obstetrician and pediatrician. Prompt and efficient delivery room management can minimize the sequelae of aspirated meconium and decrease the chance of perinatal asphyxia in the new born babies.

Effect of lower respiratory tract infections on peak expiratory flow rate in children admitted to Rajarajeshwari medical college hospital, Bangalore, Karnataka, India

Background: Peak expiratory flow rate is the simplest , cost effective and easily available test to assess the respiratory function. PEFR is measured by a peak expiratory flow meter. Measurement of PEFR is most commonly used for asthmatic patients. To evaluate the effect of lower respiratory tract infection on peak expiratory flow rate in children.'Methods: PEFR were measured in eighty children suffering from LRTI by peak flow meter . Height and weight were measured. PEFR was compared with the normal charts. mean PEFR was calculated and predicted percentage of PEFR was calculated.Results: Mean PEFR in pneumonia , para pneumonic effusion, bronchiectasis, and bronchitis was 187.2 , 187.6, 171.85 and 173.1 respectively. Mean PEFR was maximally reduced in bronchiectasis and bronchitis. Mean' PEFR was reduced in female children in comparison to males with LRTI. PEFR was decreased' more in children with severe clinical presentation and with malnutrition.Conclusions: In this study , most common LRTI was pneumonia followed by parapneumonic effusion. PEFR was maximally reduced in bronchiectasis and bronchitis. Undernourished children were more affected.