Two cases of food-dependent exercise-induced anaphylaxis with different culprit foods

Food-dependent exercise-induced anaphylaxis [FDEIA] is one of the severe allergic reactions in which symptoms develop only if exercise takes place within a few hours of eating a specific food. It is important to consider FDEIA in cases of unexplained anaphylaxis as reactions can occur several hours after ingesting the culprit food [s]. We herein report the first two cases of FDEIA in the Middle East. The first one is induced by wheat, while the other by peanut. The pathophysiology, predisposing factors, diagnosis, and treatment of FDEIA are also summarized here

effects of L-thyroxin replacement therapy on bone mineral and body composition in hypothyroid children

This study aimed to detect the effects of L-T4 treatment on bone mineral and body composition in hypothyroid children, Thirty five hypothyroid patients [10 males and 25 females], mean age was 11.57 +/- 5.06 yr. Twenty six children of matched age and sex served as controls, Dual energy X-ray absorptiometry [DXA] was done to detect the bone mineral density [BMD], bone mineral content [BMC] and Z score at lumbar and femur neck regions. Body composition was also studied by DXA. Serum calcium, phosphorus, osteocalcin, osteoprotegrin and urinary deoxypyridinoline were measured. No significant differences were detected in lumbar Z score [-0.19 +/- 0.65] and femur Z score [-0.16 +/- 0.57] compared to controls [-0.33 +/- 0.75] and [-0.21 +/- 0.53] respectively. BMD and BMC are not significantly different from controls. No significant difference was detected between cases and controls as regard body composition. Positive correlation was detected between BMD and age [r 0.857, P<0.01], and with the period of treatment [r=0.766, P<0.01]. Positive correlation was existed between BMD and total body fat [r=0.693, P<0.01], and with abdominal fat [r=0.667, P<0.01]. L-T4 treatment in hypothyroid children doesn't alter bone metabolism and body composition