ABSTRACT
The objective of the present study was to determine the changes in the glucose level and lipid profile in patients with polycystic ovarian syndrome [PCOS]. Descriptive study. This study was conducted at lnstitute of Molecular Biology and Biotechnology, The University of Lahore from June 2009 to June 2010. Total 50 patients with PCOS were included and 50 age-matched control subjects were also selected for comparison. Their glucose levels and lipid profile were assessed using commercial kits. The data thus obtained was subjected to statistical analysis. Results: Significant differences [P<0.05] in fasting blood glucose level and individual parameters of lipid profile were observed in women with PCOS. A higher prevalence of hypertriglyceridemia, hypercholesterolemia, higher LDL, lower HDL and higher fasting blood glucose levels was explored in PCOS women than controls. Abnormal glucose level and lipid profile in PCOS women showed that these women are at an increased risk of developing diabetes and subsequently cardiovascular diseases.