[Ichthyosiform parapsoriasis: report of a case]

Acquired ichthyosis is a known paraneoplastic sign of lymphoproliferative malignancies with nonspecific histopathologic findings revealing no implication of the underlying neoplasm. However, ichthyosiform eruption is considered as a specific manifestation of mycosis fungoides [MF], i.e., ichthyosiform MF. There are a few reports of ichthyotic manifestation of MF, but only one report of this presentation in parapsoriasis. We present a case of ichthyosiform parapsoriasis in a 22-year-old woman with hyperpigmented ichthyosiform scaly patches on her trunk and extremities. The histopathologic findings were hyperkeratosis, parakeratosis and acanthosis with scattered lymphocytic infiltration, also could be seen in parapsoriasis. The patient responded well to oral photochemotherapy

[Hereditary leiomyomatosis and renal cell carcinoma [HLRCC syndrome]: a case report]

Recently multiple cutaneous leiomyomas, uterine leiomyoimatosis and renal cancer have been described as a cancer syndrome with autosomal dominant pattern of inheritance. We report a 79-year-old man who presented with multiple hyperkertotic erythematous nodules on his right leg with histological diagnosis of pilar leiomyoma. In his past medical history several systemic complaints such as gross hematuria, weight loss and bone pain were noted and further investigation confirmed histological diagnosis of metastatic papillary renal cell carcinoma. History of uterine leiomyomas and hysterectomy was peresent in his sister. All these findings in this case can be attributed to hereditary leiomyomatosis and renal cell carcinoma syndrome [HLRCC Syndrome]