ABSTRACT
From the time of immemorial people have used various plant extracts in their own ethnic therapeutic system. Mango (Mangifera indica) is adorned all over the world as a fruit. But these plants have some medicinal utility also. The present research work is done to evaluate the antidiabetic effect of mango leaf on albino rat. Phytochemical tests are made with ethanolic extract of mango leaf. Albino rats were treated with ethanolic plant extract at the dose of 100,200 and 400 mg/kg body weight respectively. Another group of diabetic rats are given standard insulin dose as hypoglycemic agent. The blood sugar levels are monitored separately for different groups at different time periods. A significant reduction in blood glucose level is observed at 200mg/kg level after four hours of leaf extract application. It shows that Mangifera leaf is almost equipotent to insulin in its ability to reduce blood sugar.
ABSTRACT
Neurotoxic effect of BHC, the organochlorine pesticide in Heteropneustes fossilis has been studied exposing at the dose concentrations of 1 ppm, 5 ppm and 10 ppm in lab aquarium for 96 hours over a period of one year. The results showed the behavioural abnormalities in different exposure concentrations such as dysfunction of endocrine gland, excretion of mucus, dispigmentation, sign of restlessness, erratic swimming with rapid jurkey movement, spiralling and convolution showing severe effect in central nervous system. Therefore an attempt has been made for monitoring of BHC residues viz. alpha, beta, gamma isomers in the brain tissue exposed to different sublethal concentrations using Gas liquid chromatography. The mean values of isomers were found to be 1.587 microg/gm for 1 ppm, 2.993 microg/gm for 5 ppm and 3.78 microg/gm for 10 ppm test group. Severe behavioural abnormalities were recorded at high dose concentration of pesticides with higher accumulation of pesticide residues in brain tissue.