ABSTRACT
The present study was carried out on 100 patients with acute myocardial infarction (AMI) being treated with angiotensin converting enzyme (ACE) inhibitor and another 80 patients with conventional treatment but without ACE inhibitor during the period from May 1, 1995 to August 7, 1996 in Medical College, Calcutta. Clinical and other laboratory investigations including echocardiographic parameters were noted and recorded meticulously within 24-48 hours after AMI and repeated at 4th week. The present study based on non-invasive methods other than haemodynamic methods has shown that the echocardiographic assessment of left ventricular functional parameters after 4 weeks of ACE inhibitor therapy (n = 100) were better in treated group in comparison to control group without ACE inhibitor (n = 80) and the difference was statistically significant at 99% level of confidence. Overall mortality was 4% in ACE inhibitor group and 8.75% in the control group. This short term study with early intervention with ACE inhibitor within 48 hours of AMI has shown statistically significant evidence of beneficial effect of ACE inhibitor in improving the ventricular functional parameters and also reducing short term mortality from cardiac cause within 4 weeks compared to the group not receiving ACE inhibitors.
Subject(s)
Adult , Aged , Aged, 80 and over , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Captopril/therapeutic use , Female , Humans , Male , Middle Aged , Myocardial Infarction/drug therapy , Time Factors , Treatment Outcome , Ventricular Function, Left/drug effectsABSTRACT
Rheumatic mitral stenosis is frequently encountered in our country. It affects younger population and is a major cause of morbidity Mitral valvotomy is the definitive therapy for this disease and can be achieved by closed mitral commissurotomy (CMC), open mitral commissurotomy (OMC) or by percutaneous transluminal mitral valvuloplasty (PTMV). Compared to CMC, PTMV is less invasive but more expensive at this moment. With the reduction of cost, PTMV may become the procedure of choice for the treatment of rheumatic mitral stenosis in future.
Subject(s)
Adolescent , Adult , Aged , /adverse effects , Cardiac Surgical Procedures/adverse effects , Cost-Benefit Analysis , Female , Humans , India , Male , Middle Aged , Mitral Valve Stenosis/etiology , Rheumatic Heart Disease/complications , Treatment OutcomeABSTRACT
Eighty patients suffering from stroke were studied on the setting of clinical and computerised tomography (CT) scan findings and were followed up to 6 months. Even though some of the clinical and CT scan findings are found to be important in prediction of outcome of stroke patients, clinical assessment appears to be more important.
Subject(s)
Activities of Daily Living , Aged , Brain Ischemia/diagnosis , Cerebral Hemorrhage/diagnosis , Cerebral Infarction/mortality , Female , Follow-Up Studies , Hemiplegia/classification , Humans , Male , Middle Aged , Neurologic Examination/methods , Predictive Value of Tests , Prognosis , Recovery of Function , Survival Rate , Tomography, X-Ray ComputedABSTRACT
The present study revealed that 30.5% of acute infective hepatitis were due to the infection of Hepatitis B virus (HBV) however, 8% controls also showed HBV positivity. The possible route of infection of HBV in our country were Parenteral in 51.9%, Sexual in 24% and Unidentified in 24.1% cases. HBV marker positivity was 45.5% amongst health care workers 33.3% in recipients of multiple blood and blood product transfusion, 25% in sexual partners and their children, 20% in S.T.D. clinic attendants and 10% in patients on haemodialysis.
Subject(s)
Acute Disease , Allied Health Personnel/statistics & numerical data , Blood Transfusion/adverse effects , Female , Hepatitis B/diagnosis , Hepatitis B Surface Antigens/blood , Hepatitis B virus/isolation & purification , Humans , Incidence , India/epidemiology , Male , Needlestick Injuries , Risk , Sexual Behavior , Urban HealthABSTRACT
This study aimed to assess the prevalence of endoscopic and histological gastroduodenitis as well as helicobacter-like organisms in patients with peptic ulcer. After diagnostic endoscopy, gastroduodenal biopsy specimens were taken from thirty patients (n = 30) with clinical and endoscopic diagnosis of peptic ulcer (duodenal ulcer = 25, gastric ulcer = 5). Endoscopic gastroduodenitis occurred in 18 patients (60%). Histological gastritis was detected in the gastric body or antrum in 25 (83%) and duodenitis in 17 (57%) patients. There was significant correlation between endoscopic and histological gastritis (p < 0.05). Helicobacter-like organisms occurred in 73% of the patients with peptic ulcer and in 88% of the antral biopsy specimens showing antral gastritis. Presence of helicobacter-like organisms was in particular associated with acute on chronic gastritis compared to chronic gastritis (p < 0.01). Moreover the patients with gastritis were found to belong to the older age group and 81.8% had blood group O +ve (p < 0.01 and p < 0.05 respectively). We conclude that presence of helicobacter-like organisms in patients with peptic ulcer is significantly associated with acute on chronic gastritis.