ABSTRACT
PURPOSE: The objective of this study was to evaluate the significance of urinary Nuclear Matrix Protein22(NMP22) in patients wish bladder tumor as a diagnostic test MATERIALS AND METHODS: A total persons were divided into three groups. First group were 26 patients with bladder tumor, second group were 31 persons of normal control, third group were 28 patients with UTI(urinary tract infection). NMP22 was assayed using a commercial test kit. RESULTS: Mean NMP22 in bladder tumor group(50.6units/ml) was significantly higher than mean NMP22 in normal control group(8.4units/ml). But, mean NMP22 in bladder tumor group was not significantly higher than mean NMP22 in UTI group(47.3units/ml). Mean NMP22 did not correlate with tumor stage or tumor grade in patients with bladder tumor(p> 0.05). Sensitivity, specificity, positive and negative predictive value of NMP22 in bladder tumor(cut-of value: 10units/ml) were 73.1%(19/26), 67.7%(21/31), 65.5%(19/29) and 75%(21/28), respectively. Sensitivity of urine cytology were 50%(13/26) in the bladder tumor groups. CONCLUSIONS: Our data suggest that NMP22 in patient with bladder tumor could be a good diagnostic test. High NMP22 level in patients with UTI, however, might be decrease the availability of MMP22 in diagnosis of bladder tumor.
Subject(s)
Humans , Diagnosis , Diagnostic Tests, Routine , Nuclear Matrix , Sensitivity and Specificity , Urinary Bladder Neoplasms , Urinary BladderABSTRACT
Bladder stone formation may be associated with the intravesical foreign body. Frequency of bladder foreign body in female is less than male. We present a case of bladder stone formation for nylon suture materials in a 47-year-old female patient who has been treated by bladder neck suspension for stress incontinence. Patient was successfully treated by surgical removal of suture materials without recurrence of stress incontinence.
Subject(s)
Female , Humans , Male , Middle Aged , Foreign Bodies , Neck , Nylons , Recurrence , Sutures , Urinary Bladder Calculi , Urinary BladderABSTRACT
PURPOSE: This study was attemped to investigate the prognostic factors for the outcome of stage I renal cell carcinoma after radical nephrectomy. MATERIALS AND METHODS: Twenty nine patients treated from 1984 to 1995 at Kyung Hee University Medical Center were studied retrospectively. All of them were diagnosed with pathologic Robson stage I renal cell carcinoma after radical nephrectomy. RESULTS: Males were affected three times more frequently than females. The tumor was detected on the right kidney in 15 cases, and on the left in 14. Average follow up period was 36.6 months, average disease free interval was 29.4 months and median survival was 30 months. During the follow up, 9 patients (31.0%) expired due to liver and lung metastasis at postoperate 21.6 months on average. Eleven patients (37.9%) developed distant metastasis in the follow up. There was no local recurrence of tumor. Seventeen patients were diagnosed incidentally without clinical symptoms. In our retrospective study for stage I renal cell carcinoma, there were no predictive prognostic parameters for predicting the outcome of patients, except for the incidental diagnosis of the tumor. CONCLUSIONS: These results suggest that incidental diagnosis of the tumor may be the most important prognostic factor for the outcome of stage I renal cell carcinoma. Although the patients were confirmed as stage I renal cell carcinoma pathologically after radical nephrectomy, close follow up is very important, because of high incidence of metastasis. We recommand that chest X-ray, abdominal ultrasonogram and bone scan should be checked at 3 months interval for postoperative one year even though stage I renal cell carcinoma.
Subject(s)
Female , Humans , Male , Academic Medical Centers , Carcinoma, Renal Cell , Diagnosis , Early Diagnosis , Follow-Up Studies , Incidence , Kidney , Liver , Lung , Neoplasm Metastasis , Nephrectomy , Recurrence , Retrospective Studies , Thorax , UltrasonographyABSTRACT
We report a case of primary fibroepithelial polyp of the right midureter. The patient was a 41-year-old-woman, complaining of right flank pain. An excretory urogram revealed right hydronephrosis and a filling defect of the the right midureter. The filling defect was produced by a large fibroepithelial polyp that was diagnosed and removed by ureteroscopy without open surgery. Large fibroepithelial ureteral polyps are relatively rare and ureteroscopy is the gold standard of diagnosis for ureteral filling defect.
Subject(s)
Adult , Female , Humans , Endoscopy , Polyps/pathology , Ureter/pathology , Ureteral Neoplasms/pathology , UreteroscopyABSTRACT
Renal cell Carcinoma is an unusual cancer with the propensity to invade not only the renal vein but to propagate into the inferior vena cava(IVC) as a tumor thrombus. No tumor thrombus extending to the IVC was seen in a renal cell carcinoma less than 4.5 cm in the greatest diameter among 431 consecutive patients in the Mayo Clinic from January 1976 to January 1992. The present case was a 3.5 cm in size small renal cell carcinoma on the right upper pole which had a tumor thrombus which extended to the inferior vena cava.