ABSTRACT
Objective To explore the relationship between antibiotic application time and delivery outcome after the premature rupture of membranes,and to explore the effect of using antibiotics to delivery outcome.Methods 474 premature rupture of fetal membranes parturient who deliver in our desk work were selected as study objects.According to the time of premature rupture of membranes,the patients were dividwd into groups.The patients that bear children within 12h after the membrane rupture are divided into A group.A group had 284 cases and they were randomly divided into two groups,A1 group and A2 group,both of which had 142 cases.The patients that beared children within 12 ～ 24h after the membrane rupture were divided into B group.B group had 120 cases.The patients that beared children 24h after the membrane rupture were divided into C group.C group had 70 cases.A2 group,B group and C group were all given antibiotic intravenous infusion,A1 group was not given that.The pregnancy outcome was observed.Results B group and A group,C group and A group had significant differences in the mode of delivery,fetal distress,neonatal asphyxia,chorioamnionitis incidence (all P ＜ 0.05).A2 group and A1 group had no significant differences in the mode of delivery,fetal distress,neonatal asphyxia,chorioamnionitis incidence (all P ＞ 0.05).Conclusion If there are clear evidence which can prove maternal have infected within 12h after the membrane rupture,we can choose not to use antibiotics.And whether using antibiotics or not can not affect the delivery outcome.