Research progress on separation of natural anthocyanin by liquid-liquid partition chromatography and combination with liquid chromatography / 中草药

Liquid-liquid partition chromatography (LLC) is a continuous and efficient chromatography technique now widely used in the field of natural products. Natural anthocyanin is a flavonoid natural pigment with many physiological activities. Anthocyanin is very unstable and LLC has been widely used in the separation of natural anthocyanin because of its mild operating conditions and the avoidance of irreversible adsorption of samples. The research progress on separation of natural anthocyanin by LLC and combination with liquid chromatography from 2010 to 2019 is reviewed in this paper.