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1.
Chinese Journal of Tissue Engineering Research ; (53): 2672-2676, 2015.
Article in Chinese | WPRIM | ID: wpr-465298

ABSTRACT

BACKGROUND:In recent years,artificial cervical disc replacement surgery as a new method for the treatment of cervical disease has gradualy been accepted and understood,but relevant complications have gradualy attracted attention.OBJECTIVE:To investigate the clinical outcomes of artificial cervical disc replacement in the treatment of cervical disease and the range of motion of the replacement segment.METHODS: A total of 25 patients with artificial cervical disc replacement in the treatment of cervical spondylosis,who were treated in the Department of Orthopedics,Air Force General Hospital of Chinese PLA from August 2006 to April 2012,were enroled in this study,including 15 males and 10 females,aged 31-76 years,averagely 51.04 years.There were 6 cases of double segments and 19 cases of single segment.They were folowed up for 24 to 93 months.Clinical results were assessed using the Japanese Orthopaedic Association score,cervical dysfunction index and pain visual analog scale scores.Imaging was used to observe range of motion,cervical curvature,heterotopic ossification,and degeneration of adjacent segments.RESULTS AND CONCLUSION:Neurological function in al patients was improved to different degrees.One case suffered from mild heterotopic ossification,but no clinical symptoms were found.No significant difference in range of motion of surgical segment,and range of motion of upper and lower adjacent segments was detected between pre-replacement and final folow-up results (P>0.05).No significant difference in range of motion of C2-C7 was found between pre-replacement and final folow-up results (P>0.05).Japanese Orthopaedic Association score,cervical dysfunction index and pain visual analog scale scores were significantly improved during final folow-up compared with pre-replacement (P<0.05).These results indicated that artificial cervical disc replacement in the treatment of cervical disease can achieve better clinical efficacy,can keep the range of motion of replacement segment and avoid the accelerated degeneration of adjacent segments.

2.
Chinese Medical Equipment Journal ; (6)2003.
Article in Chinese | WPRIM | ID: wpr-596373

ABSTRACT

Objective To research and make one kind of intravascular soluble hollow stent for vascular anastomosis. Methods According to the chemical industry, CaCl2, polyethylene glycol (PEG)and gelatin were used to make one kind of intravascular soluble hollow stent for vascular anastomosis, whose surface was covered with CaCl2 membrane(CaCl2 hollow stent). After putting the stent into the two cut sides of vascular, the author put the two sides together, and dropped alginic acid sodium solution, CaCl2 solution, and glue respectively. As soon as the glue solidified, the anastomosis was finished. Results The CaCl2 hollow stent could not only support the cannel of vascular, but also generate two membrane in the two side of anastomosis site. Thus the thickness of sealant was increased. It was effective to prevent leaking of cyanoacrylate glue and its toxicity. Conclusion The CaCl2 hollow stent can generate two membrane in the two side of anastomosis site, and could increase seal effectively. Using this stent could improve the anastomosis patency by increasing the sealant thickness, and preventing leakage of cyanoacrylate glue and its toxicity.

3.
Chinese Medical Equipment Journal ; (6)2003.
Article in Chinese | WPRIM | ID: wpr-596088

ABSTRACT

Objective To research and make one kind of sealant gel to prevent glue from leaking effectively,and protect vascular anastomosis site,raise the vascular anastomosis patency.Methods The experiment was carried out based on theory and methods in chemistry;According to the membrane performance,the membrane water solubility,and other characters,the author took experiment on the alginic acid sodium,chitsan,the gelatin and other biological materials.Results Through the experiment by membrane performance,the alginic acid sodium met the requirement,which became the membrane with the CaCl2 reaction at once.Its membrane was not dissolved in the water.And the characters of its 1%-3% solution were good on fluidity and surface contact angle determines.The biological compatibility of the compound of it with 20% CaCl2 solution was good.Conclusion The characters of the composition,which is double component sealant made from 1-3% alginic acid sodium and 20%CaCl2 solution,is best in the biological experiment.Before new medical glue appeared in clinical,this gel is hopeful to be applied in clinic and provide theory basis for clinical anastomosis.

4.
Medical Journal of Chinese People's Liberation Army ; (12)2001.
Article in Chinese | WPRIM | ID: wpr-555407

ABSTRACT

Objective The complications of internal fication for calcaneal fracture were summarized and discussed to increase awareness of these complications, and to improve decision making and efficacy of the treatment. Methods The patients admitted to our hospital from October 1997 to June 2003 were followed up. The fracture in 68 feet (66 patients) was treated with open reduction and internal fixation (ORIF) using steel plate. The complications associated with ORIF were analyzed and discussed as to etiology, incidence, diagnosis, prevention and treatment. Results The patients were followed up for 7 to 57 months. Complications were found in 14 cases, including postoperative wound dehiscence in 5 (infection in 2), malunion (failure to achieve reduction) and arthritis in 9, accompanied by nerve injury in 6. The percentage of complication was 20 6%. With timely treatment, good function was regained in most of the patients. Conclusion Should attention be paid to the operation, many complications could be avoided. ORIF with plate is one ot the options for the treatment of this fracture, but the operative technic and the device should be improved. As the anatomy of the calcaneus is different from a long bone, it is unsuitable to apply the principle and device that are used in the internal fixation of a long bone to this fracture. The plate and screws used in the fixation of the calcaneal fracture can not give enough support

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