ABSTRACT
Objective To investigate the value of multiple parameter analysis in spectral CT scanning for the diagnosis of pulmonary nodules or masses.Methods The spectral CT scanning data in arterial phase of 319 patients with pulmonary nodules or masses confirmed by pathology and/or follow-up were analyzed retrospectively.The patients were divided into 3 groups:inflammatory group,lung cancer group and tuberculosis group.The Iodine(water)concentration,water(Iodine)concentration,the effective atomic number and the CT value of 60,70 and 80 keV single energy in the leisons were measured.One way A NOVA and LSD-t test were used for statistical analysis.Results One way A NOVA showed that the Iodine(water)concentration,water(Iodine)concentration,the effective atomic number and the CT value of 60,70 and 80 keV single energy among 3 groups in the arterial phase were all statistically different(P<0.05).T he LSD-t test showed there were statistical differences of Iodine content and effective atomic number between tuberculosis group and inflammatory group,lung cancer group and inflammation group(P<0.05).There were statistical differences between tuberculosis group and lung cancer group,inflammation group and lung cancer group in water concentration(P<0.05).The statistical differences in CT value of 60,70 and 80 keV single energy between tuberculosis group and inflammatory group,inflammation group and tuberculosis group were also found(P<0.05).Conclusion Multiple parameter analysis of spectral CT scanning in arterial phase could attribute to the diagnosis and differential diagnosis of pulmonary nodules or masses.