ABSTRACT
Both the presence of owned dogs and stray dogs allows the spread of Toxocara, a parasite whose eggs can be found in soil, water and food. Animals, including horses, serve as definitive and paratenic hosts. In México, where consumption of horse meat is common, Toxocara is a zoonotic parasite. The aim of this study was to identify the presence of anti-Toxocara antibodies in work horses and horses intended for human consumption by ELISA. ELISA was chosen for analysis as paratenic hosts do not shed Toxocara eggs in their feces. Blood samples were collected from a total of 188 horses, 94 of which were work horses and 94 horses from the slaughter house. Samples were analyzed by ELISA, and the general equine seroprevalence was found to be 44.6% (n = 188). Adult horses for slaughter had a 61.7% greater presence of anti-Toxocara antibodies (p = 0.006). Toxocara IgG antibodies were found in horses, confirming that horses are paratenic hosts and possible sources of infection for other animals and people.(AU)
Tanto a presença de cães com dono quanto de cães vadios permitem a disseminação de Toxocara, e o parasita está presente no solo, na água e nos alimentos. Animais, incluindo cavalos, apresentam-se como hospedeiros definitivos e paratênicos. No México, o consumo de carne de cavalo é comum, e Toxocara é um parasita zoonótico. ELISA foi escolhido para análise, já que hospedeiros paratênicos não jogam ovos de Toxocara em suas fezes. O objetivo deste estudo foi identificar a presença de anticorpos anti-Toxocara por ELISA, em cavalos de trabalho e em cavalos para o consumo humano. As amostras de sangue foram retiradas de 188 cavalos: 94 cavalos de trabalho e 94 cavalos de trabalho do matadouro. Soros dos animais foram analisados por ELISA e 44,6% dos equinos apresentaram anticorpos anti-Toxocara. Cavalos adultos para abate têm 61,7% mais elevada a presença de anticorpos anti-Toxocara (P = 0,006). Anticorpos IgG Toxocara foram encontrados em cavalos, confirmando cavalos paratênicos como hospedeiros e possíveis fontes de infecção para outros animais e pessoas.(AU)
Subject(s)
Animals , Toxocara/classification , Immunoglobulin G/classification , Horses/immunology , ZoonosesABSTRACT
Several biological processes are involved in the oxidative stress present in diabetes mellitus; among them we can find glucose autooxidation, proteins glycation and decreased antioxidant defenses. Free radicals yielded at mitochondrial level could be a trigger to unchain the vicious circle of the oxidative stress in diabetes mellitus. Aims: to determine antioxidant systems alterations and indicators of oxidative damage on lipids and proteins in patients with type II Diabetes and a control group. Materials and Methods: It was analyzed 120 serum samples; 60 from patients that suffer type II diabetic from endocrinology surgery belonging Casa de atención al paciente diabéticoin Santa Clara, Villa Clara and 60 samples from healthy individuals used as control group. Spectrofotometric techniques were used to assess levels of Superoxide dismutase and Catalase activity as well as concentrations of reduced glutathione, malonildialdehide and advanced products of proteins Oxidation. Results were compared using the statistical software SPSS. Results: Diabetes type 2 patients showed decreased of Superoxide Dismutase and Catalase enzymatic activity (p = 0,003) and (p = 0,013) respectively as well as and reduced Glutathione levels (p = 0,038). Malondialdehide and Advanced Products of Proteins Oxidation were increased (p = 0,000) in diabetics patients compared with control group. Conclusions: it was found redox alterations in patients that suffer type 2 Diabetes. These alterations are evidenced by a reduced antioxidant enzymatic system and damage on macromolecules such as lipids and proteins...
Subject(s)
Humans , Male , Adult , Female , Middle Aged , /enzymology , /metabolism , Oxidative Stress/physiology , Antioxidants/physiology , Case-Control Studies , Catalase/physiology , /blood , Free Radicals , Glutathione/blood , Malondialdehyde/blood , Superoxide Dismutase/physiologyABSTRACT
Analizamos epidemiologicamente la insuficiencia Renal Cronica. (I.R.C.T.), haciendo una breve resena historica de la evolucion del trasplante renal (T.R.), en el mundo y en Bolivia. Se describe el primer trasplante renal efectuado con exito en Santa Cruz, 9 meses despues y las realizado; se comentan sus antecedentes y las perspectivas del procedimiento en el medio.
Subject(s)
Humans , Male , Adult , Kidney Transplantation/physiology , Kidney Transplantation/rehabilitation , Renal Insufficiency, Chronic/surgery , Renal Insufficiency, Chronic/nursing , Kidney Transplantation/instrumentation , Kidney Diseases/diagnosisABSTRACT
Os autores relatam um caso de paciente com 12 anos de idade, do sexo feminino, com diagnostico de pericardite constritiva desde os 2 anos, na qual foi verificada presenca de banda pericardica constritiva, confirmada no ato cirurgico. Ressaltaram a precocidade do aparecimento dos sintomas, bem como a raridade desta doenca nesta faixa etaria. Discutem a etiologia, histopatologia, quadro clinico metodos complementares de investigacao e tratamento