ABSTRACT
Background: hepatocellular carcinoma [HCC] is one of the most common malignancies worldwide and it is one of the major causes of death, because of its high frequency and poor prognosis. Hepatocellular carcinoma is now a common malignancy in Egypt which usually develops on top of liver cirrhosis secondary to viral infection, as hepatitis C viruses increased the risk of HCC in the Egyptian patients
Aim of the Work: was to verify the possibility of using the plasma squamous cell carcinoma antigen level as a tumor marker for hepatocellular carcinoma and to evaluate its prognostic value in management of HCC
Patients and Methods: the study included 60 subjects divided into three groups: group I was 30 patients with hepatocellular carcinomas, group II was 15 patients with liver cirrhosis and group III was 15 normal subjects serving as a control group
Results: the plasma SCCA level was significantly higher in group I patients [with HCC], than in the group II patients [cirrhosis] and control group. SCCA showed direct significant correlation with the most of laboratory data specially AST, INR, number and size of lesion
Conclusion: plasma SCCA is a sensitive and specific serum marker for the diagnosis of HCC and combination of AFP and SCCA in screening and diagnosis of HCC yielded a better sensitivity in diagnosis of HCC
ABSTRACT
Abstract Introduction Themain histological features of the nasalmucosa in choanal atresia are distorted cilia, marked increase of mucous submucosal glands associated with marked reduction of goblet cell density, and lymphocytic cellular infiltration. Objective To study the nasal mucosal changes in cases of choanal atresia after successful repair compared with pre-repair mucosal histological features. Methods Tissue samples were taken from the inferior turbinate of 3 patients (1 bilateral and 2 unilateral) who were successfully operated. Then, the biopsies were subjected to histopathological, histochemical and immunohistochemical studies. After that, the results were compared with pre-repair findings in the choanal atresia side and in the normal side. Results Four biopsies (4 repaired choanal atresia sides) of the mucosa of the inferior turbinate revealed that 1 patient (who had a bilateral choanal atresia repaired), after achieving a patent choana for 8 months, had not completely recovered a normal nasal mucosa. The other 2 patients, after 18 and 23 months of achieving a patent choana, showed normal nasal cavities. Conclusion The main histological features of the nasal mucosa in choanal atresia could be reversed by surgery, making the patients regain their choanal patency, with their mucosae changing back to normal gradually with time.
ABSTRACT
This study was done on 12 patients [8 males and 4 females] diagnosed as Bell's palsy referred to E.N.T department of Al Jahra hospitals. All patients subjected to the following: Clinical and Neurophysiologic Investigations, Electroneurographic tests and MRI. The aims of this study were to better define the role of Gd-MRI with facial palsy with regard to patterns of Gd-MRI enhancement, utility for correlation with clinical and ele The aims of this study were to better define the role of Gd-MRI with IFP with regard to patterns of Gd-MRI enhancement, utility for correlation with clinical and electrophysiological investigation, and appropriate indications for its use. ctrophysilogical investigation, and appropriate indications for its use