ABSTRACT
Experimental gastric ulcer rat was prepared by submucosal injection of acetic acid (0.1ml) and the number of the low resistance point and the degree of sweating were measured at 3, 7, 14 and 21 days after the operation. The stomach and the auricular skin at the low resistance point were fixed then examined histologically.<br>The low resistance points detected by the square pulse method were gradually increased with the development of gastric ulcer then decreased to the control level at 21 days after the operation. The degree of sweating of the auricular skin also increased accompanied with visceral disorder. The parallel change of the low resistance point and sweating was slightly diminished by the bilateral section of the superior cervical ganglion. No characteristic histological changes of the skin was observed in the low resistance point as far as we examined.<br>These results suggest that the increase of the low resistance points accompanied with the gastric ulcer is caused by the neural and humoral activation of the sweating gland.