ABSTRACT
We present the case of an infant with oral cancer that developed in the 3rd month of life, following which oral feeding became difficult. In the 11th month of life, the right side of the mandible was resected surgically and movement on the right side of the mandible was restricted because of the compression caused by the rectus abdominis myocutaneous flap used for reconstruction. We initiated rehabilitation for the initial acquisition of eating functions so that the patient would be able to ingest baby food despite having an organic disorder in the oral cavity.Postoperative dysphagia in adult oral cancer is an organic disorder that occurs after acquisition of a normal swallowing pattern, whereas postoperative dysphagia in pediatric oral cancer is an organic disorder that occurs during the initial acquisition of eating functions. At present, the rehabilitation approach has not been established.From 12 months of age in this patient, we evaluated training methods that were easily accepted by children, including postoperative oral function evaluation, with the goal of the initial acquisition of eating functions. We approached postoperative wound contracture prevention with a focus on approaches to lip insufficiency, predation, and tongue/mandibular movements. In addition, we focused on family guidance and tried to support the caretaker's correct use of methods established during training.
ABSTRACT
To determine the effect of material factors on Ca-P biomaterial-induced osteogenesis, six kinds of biphasic calcium phosphate (BCP) ceramics with different HA to TCP ratio (HA/TCP 2-8, 7-3) and different porous structure (micro-, macro- and micro/macro- porous structures) were implanted intramuscularly in rabbits. Different tissue response was detected histologically and microradiographically after the ceramic samples were implanted in the dorsal muscles of rabbits for 3 and 6 months. Obvious bone formation was found in two kinds of ceramics with the same micro/macro-porous structure at both 3 and 6 months. In contrast, no bone formation or host tissue invasion was detected in two other kinds of ceramics with only micro-porous structure, even after 6 months implantation. Some bone formation was found occasionally in two kinds of ceramics with only macro-porous structure at 6 months. Bone tissue was usually formed in direct contact with the pore surface and was only located in non-dissolved porous regions. Osteocyte lacunae were seen and no pathological calcifications were observed. These results indicate that micro- and macro-porous structure play an important role in the osteoinduction with Ca-P ceramics. Furthermore, the results showed that the osteoinductive capacity of BCP ceramics was influenced by the different dissolution rate through changing HA/TCP ratio.