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Asia Oceania Journal of Nuclear Medicine and Biology. 2013; 1 (2): 56-59
in English | IMEMR | ID: emr-138173

ABSTRACT

A male patient in his 20s presented at our clinic with pain caused by bone metastases of the primitive neuroectodermal tumor, and Sr-89 was administrated to palliate the pain. After receiving the injection, the patient complained of a slight burning pain at the catheterized area. Slight reddening and small circular swelling [diameter, 0.5 cm] were observed at the catheterized area. Sr-89 extravasation was suspected. To estimate the amount of subcutaneous Sr-89 leakage, bremsstrahlung imaging was immediately performed. We speculated that the skin-absorbed dose from the subcutaneous Sr-89 leakage was 1.78 Gy. The mildest clinical sign of local radiation injury was erythema. The received dose was higher than 3 Gy, and the time of onset was from 2 to 3 weeks. In our patient, local radiation injuries [LRIs] did not occur. Though requiring further verification, subsequent bremsstrahlung imaging and estimation of the skin-absorbed dose from the subcutaneous Sr-89 leakage are useful in confirming Sr-89 extravasation and in the decision making for the choice of treatment strategies for LRIs caused by Sr-89 extravasation


Subject(s)
Humans , Male , Radiation Injuries/therapy , Strontium Radioisotopes/adverse effects , Decision Making , Bone Neoplasms/secondary , Neoplasm Metastasis , Neuroectodermal Tumors, Primitive , Brain Neoplasms , Extravasation of Diagnostic and Therapeutic Materials
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