ABSTRACT
Uma revisão do perfil químico e farmacológico é apresentada de espécies de Strychnos (Loganiaceae) ocorrentes na América do Sul e Central, incluindo o uso popular, as substâncias isoladas e suas atividades biológicas.
A review of the chemical and pharmacological profile of Strychnos species (Loganiaceae) found in South and in Central America is presented. It includes the folk uses, the isolated compounds as well as the pharmacological activities as reported in the literature.
ABSTRACT
The methanolic extract of leaves from Byrsonima crassa, a Brazilian medicinal plant, was analyzed by CC and HPLC. Four constituents were isolated and identified as quercetin, methyl gallate, (-)-epigallocatechin gallate and quercetin-3-O-(2-galloyl)-a-L-arabinopyranoside. The methanolic and hydromethanolic extract, as well as fractions, were evaluated regarding their possible antimicrobial activity using in vitro methods. Results showed that both extracts and fractions exhibited significant antimicrobial activity against all tested strains