ABSTRACT
To evaluate the correlation between improvement in visual acuity [VA] and the reduction in central macular thickness [CMT] after treatment in uveitic macular edema. Twenty-nine eyes of 19 consecutive patients were studied prospectively. Inclusion criteria were: [1] verification of macular edema by optical coherence tomography [OCT], [2] adequate media clarity for fundus visualization, and [3] absence of coexisting ocular disease limiting visual potential. All patients had the following ophthalmic examination: best-corrected Snellen VA, slit-lamp examination, indirect ophthalmoscopy, fundus biomicroscopy, OCT, and fluorescein angiography. There were 11 males and 8 females with a mean age of 40.58 +/- 9.5 years [range, 22 to 54 years]. Eleven patients had presumed intraocular tuberculosis, four had BehAet's disease, three had pars planitis, and one had ankylosing spondylitis. At baseline, the mean logarithm of the minimum angle of resolution [logMAR] V.A. was 0.6841 +/- 0.5186 [Snellen equivalent, 20/100], and mean CMT was 419.5 +/- 105.9 mm. All patients received adequate immunosuppressive treatment and patients with presumed intraocular tuberculosis received in addition antituberculous therapy. After a mean follow-up period of 4.3 +/- 2.8 months, the mean logMAR VA was 0.231 +/- 0.178 [Snellen equivalent, 20/30] and the mean CMT was 250.9 +/- 41.9 mm. The improvement in VA and the reduction of CMT were significant [p <0.0001 for both comparisons]. OCT is useful in monitoring the efficacy of treatment in patients with uveitic macular edema