ABSTRACT
The occurence of multiple primary malignant tumor is cansidered infrequent and the primary adenocarcinoma of the duodenal bulb is a rare conditian. The autopsy incidence of duodenal adenocarcinoma is between 0.019 and 0.5%. The first documented case of duodenal carcinoma was described by Hamburger in 1746. Increased awareness of the condition, improvement in diagnostic technics and a more aggressive surgical approach have changed this disease from a postmortem curiosity to a condition that can be treated with satisfactory results. There are several reports on the high incidence of second additinoal cancer in patients with small intestinal cancer. Recently, we have experienced a case of primary duodenal bulb adenocarcinoma with early gastric cancer in a 68 year old male patient with complaints of epigastric pain, diarrhea and body weight loss. So we report the case of primary duodenal bulb adenocarcinoma combined with early gastric cancer with a brief review of literature.