ABSTRACT
BACKGROUND: We planned to compare the effect of intravenous oxycodone and fentanyl on post-operative pain after laparoscopic hysterectomy. METHODS: We examined 60 patients were randomized to postoperative pain treatment with either oxycodone (n = 30, Group O) or fentanyl (n = 30, Group F). The patients received 10 mg oxycodone/100 microg fentanyl with ketorolac 30 mg before the end of anesthesia and then continued with patient-controlled analgesia for 48 h postoperatively. RESULTS: The accumulated oxycodone consumption was less than fentanyl during 8, 24 and 48 h postoperatively. Numeric rating score of Group O showed significantly lower than that of Group F during 30 min, 2, 4, 8 and 24 h postoperatively. The incidences of adverse reactions were similar in the two groups, though the incidence of nausea was higher in the Group O during the 24 and 48 h postoperative period. CONCLUSIONS: Oxycodone IV-PCA was more advantageous than fentanyl IV-PCA for laparoscopic hysterectomy in view of accumulated oxycodone consumption, pain control and cost beneficial effect. However, patient satisfaction was not good in the group O compared to group F.
Subject(s)
Humans , Analgesia, Patient-Controlled , Anesthesia , Fentanyl , Hysterectomy , Incidence , Ketorolac , Nausea , Oxycodone , Pain, Postoperative , Patient Satisfaction , Postoperative PeriodABSTRACT
Endometrial squamous cell carcinoma is extremely rare. In 1928 Fluhmann proposed three criteria to establish the diagnosis of endometrial squamous cell carcinoma: (1) no coexisting endometrial adenocarcinoma, (2) no connection between the endometrial tumor and the squamous epithelium of the cervix, and (3) no squamous cell carcinoma of the cervix present. More recently, the World Health Organization (WHO) updated Fluhmann's criteria by adding that the tumor must contain clear evidence of squamous differentiation, such as the presence of intercellular bridges and/or keratin. We presented a case of carcinoma in situ of endocervix and endometrial squamous cell carcinoma involving full thickness of whole endometrium with a review of literature.
Subject(s)
Female , Adenocarcinoma , Carcinoma in Situ , Carcinoma, Squamous Cell , Cervix Uteri , Diagnosis , Endometrium , Epithelium , World Health OrganizationABSTRACT
No abstract available.