ABSTRACT
Background: Ovarian stimulation is an important process in IVF. Objectives:To assess the efficacy of low dose GnRH agonist depot in combination with recombinant FSH for ovarian stimulation in IVF and evaluate the clinical pregnancy rate of this protocol. Subject and method: A prospective study recruited 60 patients undergoing IVF. The patients was injected intramuscularly with a single dose of diphereline of 1.25 mg on cycle day 21-23. Then recombinant FSH was given subcutaneously on day 3. hCG was injected intramuscularly when at least one follicle reached 18 mm in diameter. Oocytes retrieval in 36 hours and embryo 2 transfer on day after oocytes retrieval. Results: Duration of stimulation was 10.8 \xb1 0.9, average number of oocytes was 3.3 \xb1 4.7, average number of embryos was 6.5 \xb1 4.1, clinical pregnancy rate was 41.7%. Ovarian hyperstimulation rate was 5%, frozen embryo rate was 40 %. Conclusions: The use of low dose GnRH agonist depot in combination with recombinant ISH is effective for ovarian stimulation in IVF.
Subject(s)
Ovulation Induction , Embryo TransferABSTRACT
Cesarean scar pregnancy is one of the rarest forms of etopic pregnancy. We reported here the case of a 30 year old woman who had a previous preterm delivery with a dead newborn, one live birth with cesarean section and twice MVA after cesarean section. She was presented an with 8-week gestational pregnancy. Diagnosis of cesarean scar pregnancy was made by abdominal and intravaginal ultrasound. We used oocyte retrieval needle to aspirate the gestational sac under ultrasound guidance. The patient was given 4 shots of methotrexate with a dosage of 50mg every other day. Beta HCG level was monitored every 3 days during hospitalization and weekly afterward. It was found that the beta HCG levels normalized after 6 weeks and the woman\u2019s condition was stable. This case showed that the combination of ultrasound-guided gestational sac aspiration and methotrexate injection was successful in management of cesarean scar pregnancy.