ABSTRACT
Objective To compare the clinical effect and safety between transurethral green laser enucleation of the prostate and transurethral resection of the prostate (TURP) in the treatment of high-risk benign prostatic hyperplasia (BPH).Methods A total of 101 patients with high-risk BPH were selected from March 2014 to January 2016 in the Central Hospital of Xinxiang City.Among the patients,52 patients were treated with transurethral green laser enucleation of the prostate (green laser group),another 49 patients underwent TURP (TURP group).The operation time,intraoperative blood loss,the mass of resected prostate,bladder irrigation time,postoperative indwelling catheter time,postoperative hospitalization time,transurethral resection syndrome (TURS) and postoperative complications were compared between the two groups.The international prostate symptom scale (IPSS) score,quality of life (QOL) score,maximum urinary flow rate (Qmax) and postvoid residual (PVR) were compared between the two groups before and three months after operation.Results The operation time,bladder irrigation time,indwelling catheter time,postoperative hospitalization time of patients in green laser group were significant shorter than those in TURP group(P ＜ 0.05),the intraoperative blood loss in green laser group was significantly less than that in TURP group (P ＜ 0.05),and the mass of resected prostate in green laser group was significantly more than that in TURP group (P ＜ 0.05).There were no significant difference in the incidence of perioperative blood transfusion,TURS,urethral stricture,temporary urinary incontinence,postoperative infection,bladder neck contracture and retrograde ejaculation between the two groups (P ＞ 0.05).There was no significant difference in IPSS score,QOL score,Qmax and PVR between the two groups before operation (P ＞ 0.05).The IPSS score,QOL score and PVR at three months after operation were significantly lower than those before operation (P ＜ 0.05).The Qmax at three months after operation was significantly higher than that before operation (P ＜0.05).There was no significant difference in IPSS score,QOL score,Qmax and PVR between the two groups at three months after operation (P ＞ 0.05).Conclusion Transurethral green laser enucleation of the prostate and TURP for treating high-risk BPH can obtain good therapeutic effect.Transurethral green laser enucleation of the prostate in the treatment of high-risk BPH has the advantages of shorter operation time,less intraoperative bleeding,faster postoperative recovery and good safety.