ABSTRACT
OBJECTIVE: To explore the effects of Bushen Jianpi Huoxue Recipe, a compound traditional Chinese herbal medicine for tonifying the kidney, invigorating the spleen and promoting blood circulation, on tibial stress injuries in rabbits. METHODS: Thirty-five mature male rabbits were used in the experiment, and randomly divided into 7 groups: sedentary control (SC) group, 1-week exercise (E-1W) group, 2-week exercise (E-2W) group, 3-week exercise (E-3W) group, 4-week exercise (E-4W) group, 3-week exercise and 1-week Chinese herbal medicine treatment (EMT-1W) group, and 4-week exercise and 2-week Chinese herbal medicine treatment (EMT-2W) group. There were 5 rabbits in each group. A rabbit model of tibial stress injuries was established by stimulating the rabbits to jump and run within a high-voltage and low-current electronic cage. Radiologic features, bone scintigraphy, histology and electron microscopy of rabbit tibia were observed, and the content of blood parathyroid hormone (PTH), bone gla protein (BGP) and testosterone was detected by using radioimmunoassay method. RESULTS: After 2-week exercise, changes in histology and osteocytes had a tendency towards stress injuries. Serum PTH and BGP levels were remarkably increased, while serum testosterone level was lower than that in the SC group. Three- and four-week continuous exercise resulted in tibial stress injuries, and the positive changes were observed in X-ray features and radionuclide images. Compared with E-3W group, the levels of serum BGP and testosterone were decreased remarkably. A series of positive results such as prevailing negativeness of X-ray features and radionuclide images, increasing process of osteogenesis, typical osteogenic phase of osteocytes and favorable transformation of biochemical markers was shown in EMT-1W and EMT-2W groups. It also showed remarkable rising levels of serum BGP and testosterone and remarkable reducing level of serum PTH in EMT-1W and EMT-2W groups as compared with E-1W and E-2W groups. CONCLUSION: Bushen Jianpi Huoxue Recipe can prevent and treat exercise-induced tibial stress injuries by stimulating new bone formation and increasing serum testosterone level.
ABSTRACT
AIM:To detect the muscle strength and endurance of healthy young people with different sport levels using isokinetic testing technique,so as to explore the characteristics of trunk muscle function. METHODS:①120 volunteer freshmen of Grade 2005 including 60 males and 60 females were selected from Capital Institute of Physical Education,and were divided into three groups:general group,physical training group and second-class athlete group(n =40,half male and female). Cybex6000 isokinetic testing system(U.S.A) was used. ②The muscle strength of flexors and extensors trunk muscle was measured at 60?/second and 120?/second and the endurance at 120?/second. ③Peak torque,flexors/extensors peak torque ratio,endurance ratio and recovery ratio were evaluated. RESULTS:①The peak torque values of male extensors in 3 groups were higher than those of flexors;with the increase in testing velocity,the peak torque value of extensor and flexors was decreased,especially the extensor. The peak torque value of general group was lower than that of physical training group and second class athlete group(P 0.05). The change in peak torque value of female extensor and flexors was the same to males. The flexors/extensors peak torque ratio at 60?/second and 120?/second of males was less than 1,but females more than 1. ②Under the same testing velocity,the endurance ratio and recovery ratio of extensor in 3 groups were higher than those of flexors. CONCLUSION:Compared with physical training students and second class athletes,significant decrease in the waist and back muscle strength and unbalance of extensor and flexors strength are found in general students. The muscle strength and endurance of extensor in students with different sport levels are inferior to those of flexors.