ABSTRACT
Objective To investigate the level of platelet parameter of uterine cervical cancer patients and its clinical significance. Methods Seventy-four cases with cervical cancer (the observation group) from Ningde Municipal Hospital, the Affiliated Hospital of Fujian Medical University from May 2014 to May 2016 were chosen as the research subjects. Seventy-four cases of healthy people were treated as the control group. According to the International Federation of Gynecology and Obstetrics (FIGO), the observation group was divided into 15 cases under stage ⅡB(the early stage group), 59 cases of ⅡBstage and above (the middle and advanced stage group). Platelet count (Plt) and mean volume of platelet were monitored and compared by using Japan automatic blood cell analyzer. Results Plt in the observation group was higher than that in the control group [(266 ±71) × 109/L vs. (215 ±42) × 109/L, respectively], and the difference was statistically significant (t = 5.322, P＜ 0.05). The average volume of platelet in the observation group was lower than that in the control group [(9.2±1.2) fl vs. (9.9±1.3) fl, respectively], and the difference was statistically significant (t =-3.931, P ＜ 0.05); There was no statistical difference in the Plt and mean volume of platelet between the early stage group and the middle and advanced stage group (both P＞0.05). Conclusions The determination of platelet parameter has a certain clinical significance for screening and early detection of uterine cervical cancer.