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Objective To explore the clinical value of combined detection of SCC and CEA in the diagnosis of lung cancer.Methods 382 cases from January 2015 to April 2016 in the respiratory department of our hospital were selected in this survey.Among which 172 cases with lung cancer,110cases with benign lung diseases and 100 healthy person.The CEA and SCC content in serum of all these cases were determined by chemical chemiluminescence,and the diagnostic efficacy of lung cancer by CEA or SCC alone and CEA and SCC combined examination was compared.Results In lung cancer group,the serum levels of CEA and SCC content were significantly higher than those of the normal control group and lung benign disease group(P＜0.05),and benign lung disease group were significantly higher than that of the normal control group(P＜0.05).and compared with squamous cell carcinoma and small cell lung cancer,CEA has the highest content in adenocarcinoma(P＜0.05).Meanwhile,the content of SCC in squamous cell carcinoma was obviously higher than that of small cell lung cancer and adenocarcinoma(P＜0.05),The sensitivity of CEA was significantly higher than that of SCC(P＜0.05),and the sensitivity and negative predictive value in combined detection group was significantly higher than that of CEA or SCC(P＜0.05).Conclusion SCC and CEA could be used to identify different types of lung cancer,and the combination of the two methods could improve the positive diagnosis rate,facilitate the early detection of lung cancer,early treatment,has the promotion value.
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Objective To analyze the status and control effects on coal-burning-borne endemic fluorosis in Zunyi City,Guizhou Province,and to provide a scientific basis for sustainable prevention and control of endemic fluorosis.Methods All diseased villages of 5 counties of Zunyi City in 2014,survey results of the dental fluorosis of children aged 8-12,the use of improved stoves and stoves for all residents of the diseased villages,the proper drying conditions for corn and peppers,were analyzed.The diagnosis was based on "the Diagnosis of Dental Fluorosis" (WS/T 208-2011).Results Dental fluorosis of 115 840 children were examined,the prevalence rate of dental fluorosis was 5.85％ (6 773/115 840) in 5 diseased districts.A total of 444 196 households in Zunyi City were investigated,the qualified rate of improved stoves and the correct-usage rate of qualified stoves were 99.53％ (442 108/444 196) and 99.34％ (441 256/444 196),respectively;the proper drying conditions of corn and peppers was 99.26％ (440 903/444 196).Conclusions The control efficiency for coal-burning-borne fluorosis in Zunyi City is obvious.We will continue to strengthen the health intervention and post-management efforts to consolidate the results of elimination of fluorosis.
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Objective To analyze the correlation between serum lipoprotein associated phospholipase A 2(Lp‐PLA2) with five traditional inflammatory factors of TC ,TG ,LDL‐C ,hs‐CRP and Hcy in the patients with coronary heart disease(CHD) ,and to in‐vestigate the relationship between its concentration with the lesions and severity of CHD .Methods Two hundreds cases of CHD were selected as the lesion group(which was subdivide into single vessel lesion ,double vessel lesion and three vessel lesion) ,at the same time ,100 persons undergoing physical examination were selected as the control group .The correlation between Lp‐PLA2 with five traditional inflammatory factors of TC ,TG ,LDL‐C ,hs‐CRP and Hcy was analyzed .The differences of Lp‐PLA2 in the lesion group and the control group were compared and the relation between Lp‐PLA2 level with lesion vessels number was analyzed .Re‐sults Lp‐PLA2 was significantly correlated with LDL‐C ,Hcy ,TC and hs‐CRP(P0 .05) , the level of Lp‐PLA2 in the lesion group was significantly higher than that in the control group (P0 .05) .Conclusion High concentration of Lp‐PLA2 is a risk factor for coronary atherosclerosis ,but the correlation between the Lp‐PLA2 level and the severity of coronary arterial lesion needs further study .
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Objective To understand the city residents' iodine nutrition level after implementation of a new iodine concentration standard.Methods Using random sampling,four counties were selected to monitor iodine nutrition level;in every county 50 children aged 8-l0 and 20 pregnant women were selected as monitoring subjects;B ultrasound scan was used to detect goiter and children urinary iodine and salt iodine levels were tested;urinary iodine concentration of pregnant women and nursing mothers was determined.Results Thyroid of 200 children aged 8-10 years were detected,the enlargement rate of thyroid gland was 1％ (2/200);200 salt samples were tested,qualified iodized salt consumption rate was 96％ (192/200);200 copies of children urine samples were tested,the median of urinary iodine was 229.3 μg/L;80 copies urine samples of pregnant women were tested,urinary iodine median was 183.7 μg/L.Conclusions After implementation of a new standard of salt iodine content,the iodine nutrition level of children in the four counties (districts) of Zunyi is still high,but the level of iodine nutrition of pregnant women appears imbalanced.We suggest to supply different concentrations of iodized salt for different groups of people,to strengthen the monitoring,and to prevent iodine deficiency disorders.