ABSTRACT
Objective@#The aim of this study is to investigate the effect of fibreoptic endoscopic of sallowing （FEES） in the assessment of pharyngeal dysphagia in post-irradiated patients with nasopharyngeal carcinoma.@*Method@#Fifty-three NPC patients with post-irradiated underwent FEES and video fluoroscopy（VF）.The results were analyzed using the Bolus Residue Scale and Rosenbek's penetration aspiration scale.@*Result@#The agreement in the detection of penetration and aspiration between FEES and VF of liquid（κ=0.56, 95%CI 0.38-0.73） and porridge（κ=0.64, 95%CI 0.43-0.81） was "fair". The detection rates of penetration on FEES with liquid and porridge were 60% and 51%, the detection rates of aspiration on VF with liquid and porridge were 70% and 53%. There were no statistical differences. The agreement in the detection of pharyngeal residue between FEES and VF of liquid （κ=0.38, 95%CI0.12-0.62） and porridge （κ=0.66, 95%CI 0.44-0.86） was "fair". The detection rates of pharyngeal residue on FEES and VF with porridge were 43% and 45%, the difference was not statistically significant. The detection rates of pharyngeal residue on FEES and VF with liquid were 44% and 24%, and the difference was statistically significant.@*Conclusion@#FEES is an effective and valuable tool for evaluating pharyngeal dysphagia in post-irradiated patients with nasopharyngeal carcinoma.
ABSTRACT
The aim of this study is to investigate the effect of fibreoptic endoscopic of sallowing （FEES） in the assessment of pharyngeal dysphagia in post-irradiated patients with nasopharyngeal carcinoma. Fifty-three NPC patients with post-irradiated underwent FEES and video fluoroscopy（VF）.The results were analyzed using the Bolus Residue Scale and Rosenbek's penetration aspiration scale. The agreement in the detection of penetration and aspiration between FEES and VF of liquid（κ=0.56, 95% 0.38-0.73） and porridge（κ=0.64, 95% 0.43-0.81） was "fair". The detection rates of penetration on FEES with liquid and porridge were 60% and 51%, the detection rates of aspiration on VF with liquid and porridge were 70% and 53%. There were no statistical differences. The agreement in the detection of pharyngeal residue between FEES and VF of liquid （κ=0.38, 95%0.12-0.62） and porridge （κ=0.66, 95% 0.44-0.86） was "fair". The detection rates of pharyngeal residue on FEES and VF with porridge were 43% and 45%, the difference was not statistically significant. The detection rates of pharyngeal residue on FEES and VF with liquid were 44% and 24%, and the difference was statistically significant. FEES is an effective and valuable tool for evaluating pharyngeal dysphagia in post-irradiated patients with nasopharyngeal carcinoma.
ABSTRACT
Objective Toexploretheclinicalvalueofiterativedecompositionofwaterandfatwithechoasymmetryandleast-squaresestimationquantitationsequence(IDEAL-IQ)foraccurateandquantitativeevaluationofvertebraebodyfatfraction(FF)of lumbar.Methods Accordingtotheresultsofbonemineraldensity(BMD),60healthycheckers/patientsmatchingthestudycriteria weredividedintothenormalBMDgroup(groupA,n=17),thelowBMDgroup(groupB,n=18)andtheosteoporosis(OP)group (OP,groupC,n=25).Theageofthreegroupswasanalyzed.T1WI,T2WI,andIDEAL-IQsequenceswerescannedwithsagittallumbar.Rectangular ROIwereoutlinedonFatFracmaps,FFsweremeasuredthreetimesonvertebraebodyoflumbar1(L1),L2,L3,L4,L5,andtheFF ofeachlumbarwasrespectivelyaveragedtoanalyzethedifferencewithinandbetweengroups.Results Theageamongthethree groups(F=13.414,P=0.000)werestatisticallysignificantdifference.Inbothcomparisons,theagewassignificantdifferencebetweengroupA andB,aswellasbetweengroupAandC,butnotbetweengroupBandC.TheFFofL1-L5withineachgroupwerenotstatistically significantdifference(F=0.680,0.863,0.539,P=0.608,0.490,0.707),whilealldifferencesbetweeneachgroupwithFFofL1-L5 werestatisticalsignificance(F=12.758,9.646,5.195,8.048,8.849,P=0.000,0.000,0.008,0.001,0.000).Comparisonbetweenthe groups,theFFofL3andL5inthegroupAandBwerenotstatisticallydifferent,aswellastheL2,L3,L4inthegroupBandC, whiletheothersbetweentwogroupswerestatisticallysignificantdifference.Conclusion Astheageincreases,BMDgraduallydecreases,whilethe FFofL1-L5graduallyincreases.ItisofaccuratelyevaluatelumbarvertebraeFFbyIDEAL-IQ,whichmayhelppredictOP.