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Objective:To investigate magnetic resonance imaging (MRI) findings of primary ovarian leiomyoma (POL) and improve the understanding of the disease.Methods:The clinical data of four cases of POL confirmed by surgical pathology who received treatment in Huadu District People's Hospital between September 2006 and August 2018 were retrospectively analyzed. MRI manifestations and pathological features of POL were analyzed.Results:In four cases, POL occurred in unilateral ovarium and appeared to be a single quasi round mass with complete capsule and clear boundary. A solid mass was observed in three cases and a cystic solid mass in one case. Subcapsular effusion was observed in three cases with a relatively large tumor body. Typical MRI findings were iso-intensity or slight hypo-intensity signal on T 1WI, hypo-intensity signal on T 2WI and diffusion-weighted images. The solid part on enhanced scan was enhanced synchronously with the uterus. Atypical T 2WI findings included cystic changes as shown by varying degrees of hyper-intensity signal, and the cystic change area was not enhanced. The internal signal and pathological features of POL were similar to those of uterine leiomyoma. Conclusion:The research results are highly innovative and scientific. MRI is of great significance in the diagnosis and differential diagnosis of POL.
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Objective:To investigate the imaging characteristics of pregnant women complicated with posterior reversible encephalopathy syndrome(PRES), in order to improve the understanding of the disease.Methods:The clinical and imaging data of 17 pregnant patients complicated with PRES from July 2011 to July 2017 of the People′s Hospital of Huadu District in Guangzhou were analyzed retrospectively.Results:All patients were preeclampsia or eclampsia in pregnancy (5 cases with eclampsia, 12 cases with eclampsia). Among them, 8 cases underwent CT examination, 9 cases underwent MRI examination Typical imaging findings were symmetrical subcortical white matter and subcortical cerebral edema presented as irregular low density area on CT images and symmetric subcortical white matter and abnormal cortical signal on MRI fluid-attenuated inversion recovery (FLAIR)images.Diffuse-limited signals were not observed in both DWI and ADC.The location of lesions were parieto-occipital lobes[100.0%(17/17)], followed by frontallobe[88.9%(15/17)], temporal lobe[29.4%(5/17)], basal ganglia[41.2%(7/17)], corpus callosum[17.6%(3/17)], radiant crown[11.8%(2/17)]and cerebellum[11.8%(2/17)]. After symptomatic treatment, the clinical symptoms of all patients were significantly improved after 1-2 weeks, and no clinical symptoms were observed after 1-3 months of follow-up.Conclusion:The characteristic imaging features can be assessed in pregnant patients complicated with PRES, which presented as symmetrical subcortical white matter and subcortical cerebral edema, mainly involved the region supplied by posterior circulation, got good results after treatment timely.
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Objective To summarize the features of multislice spiral computed tomography (MSCT) examination of gastrointestinal stromal tumors (GISTs),and investigate the relationship between predictors and risk of MSCT examination for GISTs.Methods The clinical data of 110 patients with GISTs who were admitted to the Tianjin Medical University Cancer Institute and Hospital from July 2011 to February 2014 were retrospectively analyzed.All the patients received 64-slices spiral CT (64S-SCT) or 16-slices spiral CT (16S-SCT) scan,and the data were transported to the PACS work station for multiplanar reconstruction.All the tumor samples were collected during operation and diagnosed by morphological manifestation and immunohistochemistry of tumors.Very low,low,and medium risk of GISTs were regarded as lower risk grade,and high risk of GISTs as high risk grade.The univariate analysis and multivariate analysis about features of imaging and risk were done by chi-square test and multivariate logistic regression model.Results Tumors located at the stomach in 81 cases,small intestines in 26 cases and colorectum in 3 cases.Diameter of tumors was 0.8-25.0 cm.Smaller tumors were in round or oval shape with well demarcated boundary,and larger tumors were irregular with unclear boundary.Endo-luminal growth of lessions was detected in 25 cases,duplex growth in 35 cases and extra-luminal growth in 50 cases.Enhanced CT scan showed that most of tumors in 105 patients demostrated moderate and high enhancement,heterogeneous enhancement in 74 cases,low density sacvariable necrosis area without enhancement in 60 cases and superficial,cracked-like and deep ulcer without calcification,metastasis and ascites in 23 cases.According to the features of GISTs by MSCT examination,location of tumor,diameter,shape,boundary,growth,enhancement,cystic necrosis,ulcer and metastasis were risk factors affecting risk classification of tumors by univariate analysis (x2=7.442,49.966,31.513,46.038,13.836,16.626,23.489,8.280,6.811,P ＜0.05).Diameter of tumor more than 10 cm and ulcer were independent risk factors affecting risk classification of tumors by multivariate analysis (OR =9.927,0.070 ; 95％ confidence intewal:1.888-52.180,0.012-0.398,P ＜ 0.05).Conclusion There is a characterization in the location,diameter,shape,boundary of tumor,growth,enhancement,cystic necrosis,ulcer and metastasis,and diameter of tumor more than 10cm and ulcer are independent risk factors affecting the risk classification of GISTs.
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As a non-invasive functional radiographic imaging method, perfusion computed tomography (PCT) permits the evalu-ation of non-small-cell lung cancer (NSCLC) angiogenesis and response to therapy by demonstrating alterations in NSCLC vascularity. PCT performed shortly after initiating therapy may provide a better evaluation of physiological changes rather than conventional size as-sessment obtained by response evaluation criteria in solid tumors. Based on the angiogenesis principle of NSCLC, the main evaluation indexes of PCT are blood flow, blood volume, mean transit time, permeability surface, and peak enhancement index. The relationship between PCT and the indexes of vascular normalization may have implications for exploring the predictive model of efficacy and prognostic factors of NSCLC. The cavity of microvessel in NSCLC and expression of VEGF factors are closely related to PCT imag-ing. According to PCT assessment, pathological classification and histological type of NSCLC play significant roles. However, techni-cal limitations, reproducibility of blood flow parameters, radiation dose, and volume of contrast medium delivered to the patient are some issues in this type of investigation. With the development of PCT technology and anti-angiogenesis drugs for NSCLC, more mo-lecular imaging markers and standardized targeted therapies will be available. Such advancements will provide a wider space for the as-sessment of NSCLC treated with anti-angiogenic therapy using PCT.
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Objective:This study is to improves the understanding of adenoid cystic carcinoma (ACC) of the tracheobronchial tree by observing the multi-slice cornputed tomography (MSCT) features. Methods:The MSCT features of 19 cases with primary tra-cheobronchial ACC confirmed by histopathology were retrospectively analyzed. Results:Among the 19 cases, lesions were located in the trachea in seven cases, in the segmental and above segmental bronchi in 10 cases, in the peripheral lung in two cases. Intra-and ex-traluminal growth were observed in 15 cases (79%), whereas broad-based intraluminal lesions were exhibited in two cases (11%). Among the seven cases of tracheal ACC, the CT scans for five cases showed a notable tendency toward submucosal extension. Two cas-es manifested as a diffuse or circumferential wall thickening of the trachea, and the other three cases presented homogeneous mass fill-ing of the trachea with wall thickening. The 10 cases with bronchial ACC were manifested as intra-and extraluminal growth. Eight cas-es presented homogeneous polypoid growth toward the adjacent lumen, and seven cases presented extraluminal parts that were larger than the intraluminal parts. Among 13 contrast-enhanced examinations, three cases were without enhancement, five cases were slightly enhanced, four cases were moderately enhanced, and one case was highly enhanced. Conclusion:MSCT performances of ACC of the tracheo-bronchial tree possessed certain characteristics, such as broad-based mass, intra- and extraluminal growth, and diffuse wall thickening. CT can diagnose tumor malignancy, but the definitive diagnosis for ACC should depend on pathology.
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The purpose of this study was to research the three-dimensional displacements of implant-supported cantilever fixed partial denture (CFPD) under oblique loading. One Beagle dog was used in this experiment. Two immediate implants of ITI were inserted in the mandible of the dog, and the implant-supported CFPD which used the implants as abutments was made in vitro fresh mandible. Then the digital laser speckle technique was employed to measure the three-dimensional displacements of CFPD under different oblique loading. We found that when an oblique loading was exerted on the pontic, the displacement increased with increasing of load. Under equal loading, the displacement of the abutment near to the pontic was smaller than that of the pontic but greater than that of the abut-ment far from the pontic. When oblique loading was exerted on the abutment, the displacement of the direct loaded abutment was greater than that of the other abutment and the pontic. Under the.eeual loading, the displacement of implant-supported CFPD of loading on pontic was greater than that of loading on abutments. The experiments demonstrated that implant-supported cantilever fixed partial denture (CFPD) is an effective and advisable therapy for totally? or partially edentulous patients. However, it is also suggested that the clinicians should avoid exerting oblique loading, especially the obliqe loading of the pontic when th e CPDF is used.