ABSTRACT
Objective To evaluate the left ventricular systolic function of patients with type 2 diabetes combined with microangiopathy using two dimensional speckle tracking imaging. Methods A total of 29 simple diabetes patients from January 2016 to December in Zhejiang Chinese Medicine University Affiliated Jiaxing Hospital of Traditional Chinese Medicine (DM group), 35 diabetes patients with microvascular disease (diabetic microangiopathy group), and 35 healthy volunteers (healthy control group) were enrolled in present study. The conventional echocardiography was used to evaluated the left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVEDS), end diastolic ventricular septal thickness (IVSDD), left ventricular posterior wall end diastolic thickness (LVPWTD), left ventricular ejection fraction (LVEF), and left atrial volume index (LAVI). Using pulsed Doppler technique, the mitral early diastolic and late diastolic blood flow velocity ratio (E/A), E peak deceleration time (DCT), the organization of the mitral E wave velocity and the Doppler organization Doppler e' ratio (E/e) were measured. Automatic functional imaging was used to calculate the left ventricular apical axis, the four cavities of the apex, the two cavities of the apex and the overall mean longitudinal strain of the left ventricle. The clinical data, routine echocardiographic parameters and strain parameters among 3 groups were compared by one-way ANOVA. The Tukey HSD method was used to compare the differences between two groups. Pearson correlation analysis was used to analyze the correlation between the total mean longitudinal strain of left ventricle and the concentration of glycosylated hemoglobin, triglyceride concentration and systolic pressure. Results Among the 3 groups, the subject age, heart rate, body mass index had no significant difference. In diabetic microangiopathy group, the glycosylated hemoglobin concentration, triglyceride, systolic blood pressure were higher than that in healthy control and diabetic groups, and the differences were statistically significant (t=16.135, 8.947; t=8.777, 10.947; t=13.806, 8.278, all P＜0.05). The 3 groups had no significant differences in LVEDD, LVEDS, IVSDD, LVPWTD, DCT and LVEF. Compared with healthy controls, patients with diabetes mellitus showed decreased E/A and increased E/e; while patients with diabetic microangiopathy had decreased E/A and increased LAVI and E/e (t=13.786, 13.565; t=9.571, 11.267, 8.351, all P＜0.05). In the left ventricular apical long axis view, four chamber view, two chamber view and left ventricular overall average longitudinal strain values, increasing trend was found from healthy control group, to DM group, and to diabetic microangiopathy group, and the differences between any 2 groups were statistically significant (t=5.491, 10.907, 6.076; t=4.276, 7.011, 3.250; t=10.445, 11.633, 3.683; t=10.746, 18.731, 9.532; all P＜0.05). Pearson correlation analysis showed that the mean longitudinal strain value of left ventricle was negatively correlated with glycosylated hemoglobin concentration (r=-0.746, P=0.000), and there was no correlation with the triglyceride concentration and systolic blood pressure (r=0.079, P=0.438; r=0.067, P=0.416). Conclusion The two-dimensional speckle tracking imaging technique can effectively evaluate the left ventricular systolic function in patients with type 2 diabetic microangiopathy.
ABSTRACT
Objective To evaluate the value of transrectal real-time tissue elastography (TRTE) combined with multi parameter magnetic resonance imaging (MRI) in prostate biopsy.Methods One hundred and five patients of suspected prostate cancer patients were treated from December 2013 to December 2015 in Jiaxing Traditional Chinese Medicine Hospital. All the patients were confirmed by operation and pathology. Transrectal ultrasonography guided biopsy was performed in 105 patients after TRTE and MRI examinations, respectively, including routine 6 point needle biopsy and targeted biopsy of the positive area. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of TRTE, MRI and TRTE combined with MRI guided biopsy in the diagnosis of prostate cancer were evaluated with the results of operation and pathology as the gold standard.Results Surgical pathology confirmed that there were 44 benign prostatic nodules and 61 cases of prostate cancer in 105 cases. Fifty-two cases of prostate cancer was diagnosed by TRTE, and 45 cases were confirmed by operation and pathology. Fifty-six cases of prostate cancer was diagnosed by MRI, and 48 cases were confirmed by operation and pathology. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of diagnosing prostate cancer by TRTE, MRI and TRTE combined with MRI guided percutaneous biopsy were 71.4％, 84.0％, 78.0％, 0.865, 0.698, 78.6％, 81.8％, 80.0％, 0.857, 0.734, 90.1％, 88.6％, 89.5％,0. 916 and 0.866. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of diagnosing prostate cancer by TRTE combined with MRI guided biopsy were higher than those of TRTE and MRI. Conclusions Both TRTE and MRI have their respective advantages. The accurate localization before puncture is helpful to develop individualized program for prostate puncture, and the combining use of the two methods can improve the detection rate of prostate cancer.
ABSTRACT
Objective To probe imaging manifestations of bronchogenic cysts,as that to improve the knowledge of this disease.Methods Imaging features of congenital bronchial cyst in 32 cases confirmed by operation and pathology were analyzed.Results 4 cases of cyst localized in mediastinum ,all were liquid cyst.28 cases of cyst localized in lungs,aqmong them,22 cases were air-liquid cyst and 6 cases were air cyst,the diameter of lesions was 1~10 cm,there were 2 cases with pyothorax,4 cases with pulmonary maldevelopment,one case with brochio-pleural fistula.The cysts appeared as round or similar round,the walls of cyst was thin.The wall of cyst was obscure and there was infiltrating shadow around cysts when in company with infection.Conclusion X-ray and CT are very important in diagnosing congenital bronchial cysts,CT scan is of very help in diagnosing the compley cysts.