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Chinese Journal of Tissue Engineering Research ; (53): 10596-10600, 2008.
Article in Chinese | WPRIM | ID: wpr-406776

ABSTRACT

Cerebral palsy, a non-progressive central dyskinesis caused by a variety of reasons. is one of the major diseases resulting in serious paralysis of children nervous system. At present there is no special treatment. and most are supporting and symptomatic treatments. In recent years, with development of recombinant DNA technology and cell biology. transgenic cell lines and cell line transplantation have become new focus of study in brain transplant. Currently the experimental studies on cell transplantation, especially stem cells. in the treatment of children cerebral palsy mainly refer to newborn animals with hypoxic-ischemic brain injury at acute phase. and have made some progresses. Studies have demonstrated that stem cells can survive longest for eight months after transplanted into the brain. and can migrate to the damage a/ca and differentiate into different phenotypes of nerve cells to improve partly neuroethology disorder. However. that transplanted stem cells differentiate into minimal target neurons may be ode of main reasons that cannot achieve ideal effects.

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