ABSTRACT
Objective To compare the influence between self-monitoring of blood gluocose(SMBG)combined with digital diabetes management and traditional management mode on the related clinical indexes in the patients with type 2 diabetes mellitus(T2DM).Methods A total of 100 patients with T2DM treated in the endocrinology and metabolism outpatient department of this hospital from January 2022 to June 2022 and meeting the inclusion criteria of this study were successively included.They were divided into the experimental group and control group.The experimental group was managed by SMBG combined with digital diabetes man-agement mode,while the control group adopted the traditional management mode,the outpatient clinic follow up once a month.After 6 months of follow-up,fasting blood glucose,glycosylated hemoglobin(HbA1c),low density lipoprotein cholesterol(LDL-C)and urinary microalbumin/creatinine ratio(UACR)were compared between the two groups.Results The FBG,HbA1c,LDL-C,and UACR of the experimental group decreased after intervention when compared with baseline.Compared with the control group,the FBG[8.7(7.7,9.2)mmol/L vs.10.8(8.8,12.7)mmol/L,Z=-4.660,P＜0.001],HbA1c[6.3％(5.3,7.8)％vs.8.5％(7.2,10.0)％,Z=-5.130,P＜0.001],LDL-C[2.6(1.8,3.1)mmol/L vs.3.3(2.6,4.0)mmol/L,Z=-4.112,P＜0.001],UACR[16.1(3.5,46.5)mg/g vs.58.4(11.9,108.0)mg/g,Z=-2.220,P=0.026]for patients in the expriemental group after intervention were significantly decreased.Conclusion SMBG combined with digital diabetes management model can significantly improve the clinical indicators of patients.
ABSTRACT
Objective To investigate the correlation between serum uric acid and arterial calcification in maintenance hemodialysis patients.Methods 117 patients with maintenance hemodialysis were selected in our hospital.The blood uric acid and related clinical indexes were detected and the coronary artery calcification score (CACs) was measured by multislice spiral CT.The correlation between clinical indicators and coronary artery calcification score in hyperuricemia group and normal group was analyzed.Results The 117 patients with maintenance hemodialysis, 68 patients had elevated serum uric acid, and the incidence of hyperuricemia was 58.12％.The levels of DBP, SBP, TG, TC, hs-CRP and CACs in the hyperuricemia group were significantly higher than those in the normal group (P＜0.05).By correlation analysis, serum uric acid levels were positively correlated with TG, hs-CRP and CACs in patients (P＜0.05).The risk factors for severe vascular calcification (CACs＞400) in patients with persistent hemodialysis include hs-CRP levels, serum uric acid levels, and hypertension.Conclusion The incidence of hyperuricemia is high in continuous hemodialysis patients.There is a close relationship between serum uric acid level and coronary artery calcification.And the level of high blood uric acid is an important factor causing coronary artery calcification in patients.Therefore, the prevention of cardiovascular and cerebrovascular complications in maintenance hemodialysis patients should be paid more attention to the treatment of hyperuricemia.