ABSTRACT
Objective: In this study our main aims to know the clinicalprofile of pediatric enteric fever and the sensitivity pattern ofthe disease to drugs in this region.Methodology: This prospective observational study conductedin a tertiary care hospital at Dhaka from March to December2016 among suspected case of Enteric fever as per casedefinition. Among 212 suspected enteric fever 117 childrenwere diagnosed as enteric fever by blood culture and/or Widaltest.Results: During the study, Male: female were 1.3: 1. Maximum(70%) children were in age group 5 years or more. Most of thechildren were from urban slum area (53.6%) of Dhaka city.Cases were admitted throughout the year. Commonpresentation were fever (100%), anorexia (100%), painabdomen (74.4%) and loose motions (46.1%). The commonsigns were hepatomegaly (41.9%), hepatosplenomegaly(5.1%) coated tongue (64.9%), pallor (74.4%). Thecomplications rate was 35.9% and commonest being UTI andpneumonia. The overall positivity of Widal test was 89.7% andthe culture positivity was 32.5%. Among isolates, 94.7%wereSalmonella typhi and 5.3% Salmonella paratyphi A. Amongthem18.1% isolates were multi drug resistant.Conclusion: Enteric fever is most prevalent during summer &rainy session. WASA supplied water may play a role.Hepatomegaly is common. UTI and pneumonia are thecommonest complication. Multidrug resistant cases are not soas high as other countries. Cefixime, Ceftriaxone. Meropenamand Ofloxacine are the drugs of choice. Ciprofloxacin is stillcould be chosen for the treatment of enteric fever. Higher rateof resistant to Azithromycin is alarming.