ABSTRACT
The present study was designed to evaluate clinically and microbiologically the effects of topical application of CHLO-SITE [Chlorohexidine gel] in management of chronic periodontitis. This study was carried out on 15 patients [aged 25-55] with chronic periodontitis. They were received scaling and root planning [SRP] alone in one side and SRI plus CHLOSITE [Chlorhexidine gel] in other side. Each individual was subjected to the following measurements; [1] Evaluation of the clinical parameters pre and post treatment to detect the outcome of the treatment modality, [2] Dental plaque samples initially and at 3, 6, 9 and 12 months were obtained for microbiological evaluation showed that [1] CHLO-SITE [Chlorhexidine gel] delivered locally into periodontal diseased sites reduced all subgingival bacteria and [2] Both treatment and modality led to a highly statistically significant reduction in microbiological counts as well as clinical parameters applied. No clinical relevant side effects were observed
Subject(s)
Humans , Male , Female , Chlorhexidine , Administration, Topical , Treatment Outcome , Dental Plaque/microbiology , Chronic Disease , Follow-Up Studies , Periodontitis/microbiology , Disease ManagementABSTRACT
Treatment of chronic periodontitis affected patients is based on measures for reduction/ eradication of periodontal pathogens and alteration of the systemic and local host susceptibility. This study aimed to evaluation the effects of topical application of Atridox [Doxycycline gel] in management of chronic periodontitis. This study was carried out on 15 patients [aged 25-55] with chronic periodontitis. They were received scaling and root planning [SRP] alone in one side and SRP plus Atridox [Doxycycline gel] in other side. Each individual was subjected to the following measurements [1] Evaluation of the clinical parameters pre and post treatment to detect the outcome of the treatment modality and [2] Dental plaque samples initially and at 3, 6, 9 and 12 months were obtained for microbiological evaluation. [I] Atridox [Doxycycline gel] delivered locally into periodontal diseased sites reduced all subgingival bacteria and [2] Both treatment and modality led to a highly statistically significant reduction in microbiological counts as well as clinical parameters applied. No clinical relevant side effects were observed