ABSTRACT
In this report, we describe a patient with drug-induced liver failure who developed endogenous endophthalmitis after liver transplantation. Our patient's clinical course was so fulminant that the eye was lost in less than 1 month, without any response to therapy. Recognition of this infection is important because many patients die of disseminated Aspergillus infection, which may be detected early with bedside funduscopic examination by an ophthalmologist. Probably if the patient had referred to us earlier, it may have been possible to save the eye.
Subject(s)
Amphotericin B/therapeutic use , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/therapeutic use , Aspergillosis/diagnosis , Aspergillosis/drug therapy , Aspergillosis/microbiology , Aspergillosis/surgery , Aspergillus/isolation & purification , Ceftazidime/therapeutic use , Endophthalmitis/diagnosis , Endophthalmitis/drug therapy , Endophthalmitis/microbiology , Endophthalmitis/surgery , Eye/microbiology , Eye/pathology , Eye/diagnostic imaging , Humans , Immunosuppression Therapy/adverse effects , Liver Transplantation/adverse effects , Liver Transplantation/methods , Male , Ophthalmologic Surgical Procedures , Ophthalmoscopy , Transplantation, Homologous/adverse effects , Transplantation, Homologous/methods , Vancomycin/therapeutic use , Young AdultABSTRACT
Herein, we describe the presenting symptoms, history, ophthalmic examination, visual fields and brain magnetic resonance imaging of a patient who developed left homonymous hemianopia due to right occipital lobe hemorrhage after ingestion of sildenafil citrate (Novagra Forte). To the best of our knowledge, association of homonymous hemianopia with sildenafil usage has not been reported before.