ABSTRACT
Background: Stroke is a multifactorial disorder, the most common cause being arterial occlusion
Transcranial Doppler Ultrasonography [TCD] is a common non-invasive method available for assessment the arterial blood flow of the brain
Objective: Assessment the hemodynamic parameters of cerebral arteries, using TCD device in patients suffering ischemic stroke
Materials and Methods: This descriptive cross-sectional study was conducted on patients with ischemic stroke in 2014 in Iran after being approved by ethics committee of Researches and Technology Vice-chancellorship of Guilan University of Medical Sciences. After obtaining informed consent, all patients underwent TCD. Demographic details and TCD findings were recorded. Data were analysed in SPSS software 21 using independent t-test, Chi-square, and Fisher's exact tests. The descriptive results were presented as mean +/- SD and frequency
Results: A total of 102 patients [69 men and 33 women] with ischemic stroke and mean age of 63.72 +/- 12.64 years participated in this study
Among 49.02% of patients at least one hemodynamic abnormality was diagnosed. Small Vessel Disease [SVD], extracranial stenosis [ECS] and intracranial stenosis [ICS] were found in 29.41%, 20.59% and 11.76% of patients respectively
Abnormal Pulsatility Index [PI], Peak Systolic Velocity [PSV] and Mean Blood Flow Velocity [Vm] were reported in 32.25%, 20.59% and 9.8% of them respectively. A significant relationship was found between PSV parameter and also presence of ECS and gender [p = 0.047]
Moreover, SVD and abnormal PI were found significantly related to age [p - 0.002]
Conclusion: TCD results showed almost half of the patients with ischemic stroke were found to have at least one hemodynamic abnormality
ABSTRACT
Background: Temporal variation of stroke onset is suggested in some studies contained somewhat varieties. It is proposed that some predisposing changes occur in some ascertained times consequently resulted in stroke occurrence in some special times
Objective: To determine the circadian and circaseptan variation of stroke onset
Materials and Methods: This cross sectional study was conducted from March 2012 to February 2013 in an academic hospital in the North of Iran. All patients with acute onset of neurological symptoms were enrolled in the study after being diagnosed as a stroke patient. The diagnosis was made by a neurologist using brain imaging. Age, gender, history of diabetes and hypertension, time and date of stroke onset were recorded for all patients. The data were analysed using Chi-square test in SPSS software version 19
Results: A total of eight hundred sixty-nine patients with mean age of 67.5il2.4 years [55.6% women 44.4% men] were admitted during one year study. Eighty-five percent of stroke cases were ischemic in nature and the others were hemorrhagic type. Distribution of cases during a day was not uniform [p < 0.0001]
The peak of stroke onset occurred in the mornings [7-9 a.m.] followed by a second peak in the evenings [7-9 p.m.]
In addition, the distribution of cases during the week was also not uniform [p < 0.016]
Conclusion: Stroke occurrence has a diurnal variation probably resulted from circadian physiologic changes. Although there is a circaseptan variation in the times of stroke record, it seemingly isn't related to physiologic changes