Gastrointestinal stomal tumor: a case report

Gastrointestinal stomal tumor is a rare mesenchymal tumor of the gastrointestinal tract. Stomach and small intestine are the most common sites. Tumors originate from interstitial cells of Cajal. The preoperative and intraoperative diagnosis is usually difficult. It is necessary to base on immunohistochemical staining with antibody CD117 for definitive diagnosis. Tumor may be benign or malignant. Surgery is the first choice, and can be associated with targeted therapy, a competitive inhibitor of specific tyrosine kinase. Postoperative recurrence is rare and commonly has no complication. It is necessary to follow up by CT scan every 6 months in the first 2 years and then every 3 years

Gastrointestinal stromal tumors

Gastrointestinal Stromal Tumor (GIST) is uncommon disease with only about 3,000 to 6,000 cases diagnosed annually. Tumors can occur in any sites in gastrointestinal tract, especially in stomach (60-70%) and small intestine (20-30%) and in large intestine and oesophagus, sometime in omentum, mesenterium, behind peritonaeum, etc. The disease is common in male from 40 to 80 years old. GIST is detected randomly during examinations such as endoscopy, X-ray or CT scan of stomach, large intestine. Tumors have two kinds of cell: lozenge cell (70%) and epithelial cell (30%). GIST is divided into 4 stages. Each stage has suitable treatments as chemical therapy, radio therapy, and targeted therapy. For metastatic GIST, tumors can be removed by surgery. The 5 years survival rate is 34% in removal tumors and is 10% in remained tumors

Gastro-esophageal reflux disease

Gastro-esophageal reflux disease is a chronic disease. It develops along life, more likely recurrent, usually by some months after treatment with responses. This disease apperances in every ages, even in children and newborns, but it is more common at the age over 40 years old with the top age from 50 to 70 years old. The prevelence of disease changed from 10% to 36%. Diagnosis and treatment played an important role in preventation of complications. Pain and hemoghlobin are two complications. Causes gastro-esophageal reflux is very complex. Gastro-esophageal reflux disease is caused by many reasons and the other reasons also have different effects in each patient, even in each time on the same patient