In vitro and in vivo antimalaial activities of artesunate

Artesunate, a derivative of Quinghaosu (Artemisinine) was test for antimalarial activities against four isolates of Plasmodium falciparum in vitro and Plasmodium berghei- mouse model in vivo. The minimum inhibitory concentration of Artesunate in vitro was 6.0 p Mol per well whereas in vivo ED 90 was 1.4 mg/kg day.