ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effects of different CO(2) pneumoperitoneum conditions on renal function in rats and provide experimental evidence for improving renal graft function after transplantation.</p><p><b>METHODS</b>SD rats were randomized into 10 groups (n=12) and subject to CO(2) pneumoperitoneum at different pressures (0.67, 1.33 and 2.0 kPa) for 60 or 120 min. Serum urea nitrogen (BUN), creatinine (Cr) and N-acetyl-β-D-glocosaminidase (NAG) levels were detected after pneumoperitoneum.</p><p><b>RESULTS</b>As the pressure and time of pneumoperitoneum increased, the renal function deteriorated gradually, showing significant differences between the groups (P<0.05).</p><p><b>CONCLUSION</b>Increased pressure and prolonged duration of CO(2) pneumoperitoneum causes impairment of the renal function, suggesting the necessity of reducing the operative time and lowering the pressure of pneumoperitoneum when harvesting renal graft in living donors.</p>
Subject(s)
Animals , Female , Male , Rats , Carbon Dioxide , Kidney , Physiology , Kidney Transplantation , Laparoscopy , Methods , Nephrectomy , Methods , Pneumoperitoneum, Artificial , Methods , Rats, Sprague-Dawley , Retroperitoneal Space , General Surgery , Time Factors , Tissue and Organ Harvesting , MethodsABSTRACT
OBJECTIVE To investigate the appropriate time of replacing urine-collecting bags in allogenic kidney transplantation recipient with indwelling catheter.METHODS A total of 52 patients,accepted allogenic kidney transplantation from Jan to Dec 2006,were investigated.At 2 to 8 days after operation,the urine was collected for bacterial culture and then the urine-collecting bags changed.RESULTS There was no pathogen detected at 2 to 5 days after operation.There were 1,3 and 4 strains detected at 6,7 and 8 days after operation,respectively.Among the patients detected with pathogen,there were 5 males and 3 females.And there was 1 case of 18 to 30 years old,2 cases of 31 to 40 years old,3 cases of 41 to 50 years old,and 2 cases of 51 to 60 years old.CONCLUSIONS The appropriate time of replacing urine-collecting bags of allogenic kidney transplantation recipient is the fifth day after operation.There is no correlation between the results of urine culture and age or sex.