ABSTRACT
Objective To investigate the influence of health-care Qigong Baduanjin on mental health of patients with impaired glucose tolerance (IGT) . Methods Eighty-nine IGT patients were sampled from the physical examination center of Guangdong Provincial Hospital of Traditional Chinese Medicine, and then the subjects were randomly divided into groups A (N=30), B (N=29), C (N=30), which received health education, health education combined with walking exercise, health education combined with Baduanjin separately for one year. The scores of factors of physical and mental symptom checklist (SCL-90) were recorded before and after intervention. Results Compared to those before intervention, factor scores of interpersonal sensitivity and anxiety in group A were decreased obvi ously ( P<0.01) , factor scores of somatization, interpersonal sensitivity, depression, anxiety, terror, paranoia, psychosis in group B were decreased obviously (P<0.05 or P<0.01), and factor scores of somatization, inter-personal sensitivity, depression, anxiety, paranoia, psychosis in group C were also decreased obviously (P<0.05 or P<0.01) after intervention. Group B had lower factor scores of somatization and interpersonal sensitivity than group A (P<0.05), group C had lower factor scores of somatization, anxiety, and paranoia than group A (P<0.05 or P<0.01), group B had lower factor scores of anxiety than group C (P<0.05) . Conclusion Both Baduanjin and walking exercise can promote mental health of patients with IGT, and the effect of Baduanjin is superior to that of walking exercise.
ABSTRACT
Objective To investigate the distribution of human papillomavirus (HPV) genotypes in male patients with anogenital warts in Lishui area,Zhejiang province.Methods Tissue specimens were obtained from the lesions of 150 male patients with anogenital warts.PCR-reverse dot blot hybridization was performed to detect the presence of 3 low-risk HPV types (HPV 6,11,and 43) and 16 moderate-or high-risk HPV types (HPV 16,18,31,33,35,39,45,51,52,53,56,58,59,66,68 and CP8304) in these specimens.Chi-square test was used for statistical analysis.Results HPV was detected in 91 (60.67％) of the 150 male patients.Of the 91 positive patients,74 (81.32％) were infected by single or multiple low-risk HPV types,whereas 17 (18.68％) by single or multiple high-risk HPV types.Thirty-one (34.07％) patients harbored 2-5 HPV genotypes,including 20 (64.52％)patients infected with both low-risk and high-risk HPV types,and 6 (19.35％) patients infected with two low-risk HPV types.The coexistence of moderate-or high-risk HPV types with HPV 6 was observed in 13 (41.94％)patients,and that with HPV 11 in 6 (19.35％) patients.The most prevalent genotype was HPV 6 (28.68％,39/136),followed by HPV 11 (26.47％,36/136),16 (8.09％,11/136),52 (5.15％,7/136),53 (5.15％,7/136),51 (4.41％,6/136),58 (4.41％,6/136) and 43 (4.41％,6/136).Conclusions Low-risk HPV genotypes predominate in male patients with anogenital warts,and there are large differences in the distribution of multiple infections and HPV genotypes.
ABSTRACT
Objective To study the relationship between serum hepatitis B virus covalently closed circle DNA (HBV cccDNA) as well as liver function and liver tissue pathological changes in children with chronic hepatitis B.Methods One hundred and twenty-four HBV-DNA positive children with hepatitis B were enrolled.Among 124 patients,65 cases were HBV carriers,59 cases were chronic hepatitis (mild in 31 cases,moderate in 18 cases and severe in 10 cases).HBV cccDNA in serum and liver function were detected,46 of which underwent liver biopsy and liver tissue inflammation and fibrosis grading classification was made.Results In moderate and severe cases,positive rates of serum HBV cccDNA (77.8％,100％) were higher than those of the HBV carriers and mild cases (32.3％,54.8％) (x2 =25.429,P ＜ 0.01),indicating more severe illness in children,detection rate of serum HBV cccDNA was higher.ALT,AST,and TBIL were higher in serum HBV cccDNA positive group than those of negative group[(95.6 ± 18.2) U/L vs (52.5 ± 17.7) U/L,(88.8 ±20.3) U/L vs (48.4 ±21.4) U/L,(68.4 ±24.6) μmol/L vs (28.3 ± 23.9) μmol/L](t =15.572,10.750,17.067,P ＜ 0.01).Serum HBV cccDNA and liver inflammatory activity and fibrosis showed no significant correlationship.Conclusion Serum HBV cccDNA is a sensitive indicator of viral replication,the more severe the disease situation,the peripheral HBV cccDNA detection rate is higher.But it is not entirely consistent with liver inflammation and fibrosis,so it can not completely reflect the degree of liver damage.