Prevalence and risk factors of gestational diabetes in pregnant women, followed up at the Department of Obstetrics and Gynecology, Bach Mai Hospital, Hanoi

Background: Gestational diabetes is a special form of diabetes mellitus, which is initially diagnosed during gestation. In Vietnam, routine screens for gestational diabetes are not performed. The risk factors of the disease are not taken into account during early screening. Many pregnancies are later diagnosed when complications present themselves. Objective: To determine the prevalence and discover the risk factors for Gestational Diabetes (GD) among pregnant women, who followed up at the Department of Obstetrics and Gynecology, Bach Mai Hospital. Subject and methods: A cross-sectional, prospective study was conducted on 415 pregnant women, who had 24-28 weeks of gestation, followed up at the Department of Obstetrics and Gynecology, Bach Mai Hospital from December, 2006 to April, 2007. All were asked about the risk factors and given an oral glucose tolerance test with 75g of glucose. Results: The prevalence of GD in general population accounted for 7.9%. The prevalence of GD, who had BMI \u226523, family history with 1st degree relative of diabetes and positive glycosuria at gestational age under 24 weeks in subgroups were 25.8%, 37.8% and 55.6%, respectively. None of the pregnant women who had a child weighed \u22654.000g at the previous delivery was diagnosed as GD. However, all thepregnant women, who had history of abnormal glucose tolerance, were GD. Conclusion: Prevalence of GD is increasing. BMI\u226523, family history with 1st degree relative of diabetes and positive glycosuria at age of gestation <24 weeks are considered as high risk factors of GD.

Investigation on safety and immunogenicity of a bivalent killed oral vaccine against cholera

The study on the bivalent vaccine was carried out in 246 healthy Vietnamese volunteers’ aged from 1 to 25 years old. The results indicated that: the vaccine was well tolerated. The proportions of vaccines in both age groups exhibited anti-01 vibriocidal seroconversions, but the proportion of seroconverting was greater in children than in adults. Adult recipients of the vaccine exhibited similar to seroconversion rates of anti-01 and anti-0139 vibriocidal antibodies.