ABSTRACT
Resistance to antibiotics refers to unresponsiveness of microorganism to antimicrobial agent related to tolerance observed in higher organism. In Aden, there is still a lack of studies related to the identification of antibiotics-resistance in spite of the opening market for the spread of mostly all types of antibiotics. To perform this study, fifteen medical laboratories were selected. Most of them implicated the diffusion sensitivity method. Computer data base, using Excel-program, was [instructed for the information collected in the period from December 2007 to the end of April 2008. The total number of antibiotics standards used in these laboratories were 60. The highest number if antibiotics standard is available in Aden-diagnostic centre. Most of the collected specimens are of urine [31%].92% of them were adult and most of them were female [67%]. The most frequent pathogens of urinary infection were of gram [-] microorganisms [69%], and the most pathogen was E-coli [48%]. The most sensitive antibiotic against E-coli was Cefotaxim, while the most resistant was Ampicillin