Lipid peroxidation productts and anaemia in patients with chronic renal failure undergoing hemodialysis

Three groups of patients with chronic renal failure [CRF] undergoing hemodialysis [HD] were selected for this study. Twenty healthy individuals were selected as a control group. Plasma malondialdehyde [MDA] and 4-hydroxynonenal [HNE] were measured in these groups of patients and compared with the healthy control group. In conclusion, the present study showed that there are increased amounts of lipid peroxidation [LPO] in HD patients, particularly who showed a poor response to treatment with recombinant human erythropoietin [rhEPO] and a significant decrease in the oxidative stress occurs in patients with a good response to rhEPO therapy