A Case of Angio: Behcet's Syndrome, Arterial Occlusion Type / 대한피부과학회지

We report herein a. case of angio-Behqets syndrome, arterial occlusion type in a 31 year-old male. He had a history of scrotal ulceration, frequent oral ulceration and ocular pain with decreased visual acuity. About 8 months ago, moderately dull pain developed on the volar aspect of left index finger. Subsequently, a bean sized bluish patch developed on the previous painful area and on the ipsilateral thumb tip. Subungual splinter hemorrhages developed on the distal portions of left thumb and index finger nails at the same time. The result of saline puncture test showed the positive reaction in both intradermal and subeutaneous injections. The hrachial angiography showed an obliteration of digital artery at the second proxirnal phalanx of ulnar side.

A Study on the Solar UVA and UVB Doses at Kongju / 대한피부과학회지

An appreciation of daily and annual changes of ultraviolet radiation is important in order to optimize the conditions for climatic therapy of skin diseases or in order to minimize the harmful effects of the sun. Ultraviolet A(355nm) and ultrviolet B(290nm) doses were measured at Kongju from April to September, 1985, on two different weather conditions-clear and relatively clear. The followings were the summary of the findings. 1. On clear weather, UVA dose was peak at noon of the day and in June of the year. 2. On relatively clear weather, UVA dose was peak at 2 p.m. of the day and in July of the year. 3. UVB dose was peak at noon of July regardless of weather conditions. 4. In relatively clear weather the UVA and UVB doses decreased from those of clear weather by 29%, and 36% respectively. 5, The relative difference between the doses of UVA and UVB depended on the degree of solar zenith angle. The greater the solar zenith angle, the greater the difference. 6. In order to treat a patient with solar UVA radiation, therefore, it is suggested to have the patient expose himself to the sun around 10 a, m. and 3 p.m. to minimize the harmful effects of solar UVB. However, when one wants to treat with solar UVB radiation, it would be better to expose to the sun around noon.

A Study of the Histopathologic Changes of the Nasal Mucosa in the Patients with Leprosy / 대한피부과학회지

The route of transmission of leprosy is still unclear, Recently some authors proposed ge possibility that the bacilli discharged from nasal mucosa might be the source of infection in leprosy. This study was undertaken to evaluate the histopathologic findings of nasal mucosa in 24 fresh untreated patients with leprosy using hematoxyline and eosin stain, and Ziehl-Neelsen stain. Among 24 cases. under clinical observation, 10 cases(41,7%) complain of nasal stuffiness, 8 cases (33. 3%) has congestion, 1 case(4. 2%) was crusted and 1 case(4.2%) was ulcerated. 2 Bacterial index of nasal mucosal smear showed that 16 cases were positive, - 15 cases were 1+, 7 cases were 2+, 2 cases 3+ and 1 case was 4+ Linder H.E. stain, the histopathologic findings of (he inferior turbinate of nasal mucosa showed that 22 cases were cystic dilatation of mucous glands, 1) cases were granuloma with foamy cells cells and 14 cases were epidermal atrophy. TJnder Ziehl-Neelsen stain bacterial index of nasal mucosal biopsy showed that 21 cases were positive 3 cases were 3+, 7 cases were 4+6 cases were 5+ and 5 cases were 6+. As above results, the histopathologic findings of nasal mucosa were similar to the skin lesions of leprosy.

Two Cases of Inflammatory Linear Verrucose Epidermal Nevus / 대한피부과학회지

Inflammatory linear verrucose epidermal nevus(ILVEN) is characterized by an early age of onset, predominance in females, pruritus, unresponsiveness to treatment, and a distinctive inflammatory and psoriasiform histologic appearance. We present two cases of typical ILVEN. One of them was a 16-year-old male, who had had a mild pruritic linear verrucose patch involving the right arm which grew slowly for about 8 years. The other case was a 14-year-old girl whose lesion appeared at the age of 13. This lesion was localized on the right posterior thigh and showed linear distribution and verrucose appearance. Histopathological findings of two cases showed hyperkeratosis with foci of parakeratosis, moderate to marked acanthosis, elongation of the rete ridges, and occasional slight spongiosis, and chronic inflammatory infiltration in the dermis.

A Giant Squamous Cell Carcinoma Arising in the Lesion of Discoid Lupus Erythematosus / 대한피부과학회지

In the past, irritant or radiation therapy have been used to treat discoid lupus erythematosus, therefore malignant and proriferative change in the lesion of discoid lupus erythematosus were not uncommon. In recent year, however, because the preferred treatment of discoid lups erythematosus consisted of steroids and antimalarials, the association with squamous cell carcinoma has been extremely rare. We present a case of giant squamous cell carcinoma arising in the discoid lupus erythematosus in 39 year-old women. She had had a 20 year history of facial discoid lupus erythematoseus. In September of 1976, a thumb tip-sized tumor mass found on the right cheek and the maas grew into the adult palm size rapidly. The tumor show ulceration, serosanguinous discharge, easy bleeding, and foul oder. Histopathologically, the specimen obtained from plaques of the left cheek showed hyperkeratosis with plugging, atrophy of the stratum malpighii, a patchy, chiefly lymphoid cell infiltrate with a tendency to arrangement about the cutaneous appendages, hydropic degeneration of the basal cells, edema and vasodilatation in the dermis. The specimen obtained from tumor mass of the right cheek showed many nests consisted of well differentiated squamous cells, keratin pearls.