Analysis of YouTube Content on Oral Disease Information about the Elderly / 치위생과학회지

Background@#The elderly have, a higher disease morbidity than other age groups due to a decrease in resistance to the diseaseand have complex diseases, so care should be taken. Accordingly, it is considered important to provide information for improving the health of the elderly. Health information plays an important role in individual health promotion and education, so the degree of exposure to information about oral health of the elderly is expected to have a significant impact on understanding and acquiring information on oral content videos on the importance, prevention, and management of oral health of the elderly in the future. @*Methods@#This study analyzed video content related to oral diseases of the elderly in a total of 150 videos uploaded on YouTubefrom January 1, 2012 to May 13, 2021, using a total of three books of dental hygiene for the elderly. @*Results@#Forty-nine broadcasters accounted for the most of this information. Among the information providers, there were twodental hygienists. They accounted for 1.3% of all the information providers. The highest number of dental hygienists who broadcasted information was 42 in 2019. The average number of views was 37,303 periodontal diseases, the highest. Among the videos, dry mouth was the most common with 34 oral diseases. @*Conclusion@#The number of images for each disease varies, so it seems that information should be provided in various ways. Dentalhygienists should widely improve oral health knowledge by providing various dental hygiene management images for each oral disease to improve the oral health of the general public. In addition, based on the information of the Health Insurance Review and Assessment Service, the development and provision of content should be actively carried out so that people can obtain the information they desire.

Hyperoxygenation Ameliorates Stress-induced Neuronal and Behavioral Deficits

Hyperoxygenation therapy remediates neuronal injury and improves cognitive function in various animal models. In the present study, the optimal conditions for hyperoxygenation treatment of stress-induced maladaptive changes were investigated. Mice exposed to chronic restraint stress (CRST) produce persistent adaptive changes in genomic responses and exhibit depressive-like behaviors. Hyperoxygenation treatment with 100% O2 (HO2 ) at 2.0 atmospheres absolute (ATA) for 1 h daily for 14 days in CRST mice produces an antidepressive effect similar to that of the antidepressant imipramine. In contrast, HO2 treatment at 2.0 ATA for 1 h daily for shorter duration (3, 5, or 7 days), HO2 treatment at 1.5 ATA for 1 h daily for 14 days, or hyperbaric air treatment at 2.0 ATA (42% O2 ) for 1 h daily for 14 days is ineffective or less effective, indicating that repeated sufficient hyperoxygenation conditions are required to reverse stress-induced maladaptive changes. HO2 treatment at 2.0 ATA for 14 days restores stress-induced reductions in levels of mitochondrial copy number, stress-induced attenuation of synaptophysin-stained density of axon terminals and MAP-2-staining dendritic processes of pyramidal neurons in the hippocampus, and stress-induced reduced hippocampal neurogenesis. These results suggest that HO2 treatment at 2.0 ATA for 14 days is effective to ameliorate stress-induced neuronal and behavioral deficits.

Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood

Emerging evidence has suggested that the gut microbiota contribute to brain dysfunction, including pathological symptoms of Alzheimer disease (AD). Microbiota secrete membrane vesicles, also called extracellular vesicles (EVs), which contain bacterial genomic DNA fragments and other molecules and are distributed throughout the host body, including blood. In the present study, we investigated whether bacteria-derived EVs in blood are useful for metagenome analysis in an AD mouse model. Sequence readings of variable regions of 16S rRNA genes prepared from blood EVs in Tg-APP/PS1 mice allowed us to identify over 3,200 operational taxonomic units corresponding to gut microbiota reported in previous studies. Further analysis revealed a distinctive microbiota landscape in Tg-APP/PS1 mice, with a dramatic alteration in specific microbiota at all taxonomy levels examined. Specifically, at the phylum level, the occupancy of p_Firmicutes increased, while the occupancy of p_Proteobacteria and p_Bacteroidetes moderately decreased in Tg-APP/PS1 mice. At the genus level, the occupancy of g_Aerococcus, g_Jeotgalicoccus, g_Blautia, g_Pseudomonas and unclassified members of f_Clostridiale and f_Ruminococcaceae increased, while the occupancy of g_Lactobacillus, unclassified members of f_S24-7, and g_Corynebacterium decreased in Tg-APP/PS1 mice. A number of genus members were detected in Tg-APP/PS1 mice, but not in wild-type mice, while other genus members were detected in wild-type mice, but lost in Tg-APP/PS1 mice. The results of the present study suggest that the bodily microbiota profile is altered in Tg-APP/PS1 mice, and that blood EVs are useful for the metagenome analysis of bodily microbiota in AD.

A Structural Equation Model on Core Competencies of Nursing Students / 한국간호교육학회지

PURPOSE: The purpose of this study was to propose and test a predictive model that could explain and predict the core competencies of nursing students. METHODS: A survey using a structured questionnaire was conducted with 361 nursing students. The data was analyzed using SPSS Windows 21.0 and AMOS 21.0. RESULTS: The elements that directly influence the core competencies of nursing students were satisfaction with their academic discipline (nursing) and critical thinking disposition in which the disposition toward critical thinking directly influenced their satisfaction with nursing as an academic discipline and clinical practice. Conversely, satisfaction with clinical practice indirectly influenced core competencies through critical thinking disposition. CONCLUSION: This result provides the basic data for a competence-based curriculum intent on strengthening the core competencies (communication, problem-solving, and self-directed learning) by improving satisfaction with both clinical practice with their major and disposition toward critical thinking on the part of nursing students.

Korean Version of the 14-Item Resilience Scale (RS-14) for University Students: A Validity and Reliability Study / 정신간호학회지

PURPOSE: The purpose of this study was to verify the validity and reliability of a 14-item Resilience Scale (RS-14) by applying it to Korean university students. METHODS: The original English version of the RS-14 was translated into Korean, and the Korean version of the RS-14 was confirmed with back-translation. This was a methodological study, and data were collected from 273 students. Principal components factor analysis and Pearson correlation coefficients were used to test validity; Cronbach's alpha coefficient was used to test reliability. RESULTS: Factor analysis of 14 items revealed 2 factors with a total variance of 55.43%. The new scale correlated significantly with self-esteem (.48, p<.001) and depression (-.44, p<.001). Cronbach's coefficient was .905. CONCLUSION: The results indicate good validity and reliability for the Korean version of the RS-14. Future studies will need to further test this scale by applying it to different study populations.

Changes in longitudinal craniofacial growth in subjects with normal occlusions using the Ricketts analysis / 대한치과교정학회지

OBJECTIVE: This study was designed to define the Korean norm values for the Ricketts analysis. METHODS: In this longitudinal study, lateral cephalograms of 31 subjects with normal occlusion were taken biennially from ages 9-19 years. Cephalometric measurements were performed. Parameters for which the 10-year change did not exceed one standard deviation were defined as unchanged. The means and standard deviations for the measured parameters were determined for each age group. RESULTS: No significant changes in growth were observed in the molar relationship, incisor overjet, incisor overbite, mandibular incisor extrusion, interincisor angle, lower incisor tip (B1) to A point-Pogonion (A-PO) plane, upper incisor tip (A1) to A-PO plane, B1 inclination to A-PO, A1 inclination to A-PO, B1 inclination to Frankfurt plane (FH), convexity, lower facial height, facial axis, maxillary depth, maxillary height, palatal plane to FH, cranial deflection, ramus Xi position, or porion location. Continual changes over the 10 years of growth were observed in the maxillary first molar distal position to pterygoid true vertical plane, facial depth, mandibular plane to FH, anterior cranial length, mandibular arc, and corpus length. CONCLUSIONS: Clinicians can apply the Korean norms at age 9 as determined in this study when using the Ricketts analysis. The patient's age at the beginning of treatment and their sex should be taken into consideration when drawing visual treatment objectives.

Subjectivity on Childbearing in High School Students

PURPOSE: This study was to explore subjectivity on childbearing in high school students. METHODS: A Q-methodology which provides a method of analyzing the subjectivity of each type was used. Forty-three high school students classified 40 selected Q-statements into 9 points standard. The obtained data were analyzed by using the pc-QUANL program. RESULTS: High school students' subjectivity on childbearing were analyzed into two types: Type 1 turned out to be 'FOLS (family oriented life style)' and Type 2 'CINK (couple important no kid)'. CONCLUSION: In order to resolve such problems as low birth rate and the advanced age of the population, effective youth and adult programs, policy and institution are required. The current demographic, economic and other factors such as personal values and policies may lower birth rate. In particular, youths' need for children and birth rate tend to be lower. There are positive and negative patterns in high school students' subjectivity on childbearing. Thus, national and social efforts are needed to change negative factors into positive ones. In order to maintain positive subjectivity on childbearing in high school students, it is necessary to apply family-centered educational programs and to implement birth-friendly and realistic programs for promoting child birth.

The Experiences of Adolescents' Suffering from Cancer: Breaking out of the withdrawn Ego

PURPOSE: The purpose of this study was to describe and explore the experience of adolescents with cancer. METHODS: This study was based on the grounded theory by Strauss & Corbin (1998). The subjects were 13 adolescents including in and out-patients of a university hospital diagnosed with cancer. RESULTS: 'Getting changed' and 'getting deviated' were found to be the causal conditions. 'Inclination', 'self-reliance', and 'hope' were identified as contextual conditions, 'shrinking feeling' as the core phenomenon, 'awareness of disease', 'self-consciousness', and 'getting understanding and love' as intervening conditions, 'negligence', 'separation', 'self-management', and 'inspiration' as the strategies and 'being shirk', 'getting back', and 'going forward' as consequences. 'Breaking out of the withdrawn ego' was the core category in this study. CONCLUSION: This study provides a framework for the development of individualized nursing interventions for 'Breaking out of the withdrawn ego' to care for adolescents with cancer. Finally adolescents with cancer are 'reborn' with a more mature ego.

Subjectivity of Nursing College Students' Awareness of Gender Equality: An Application of Q-methodology

PURPOSE: This study was done to identify the awareness of gender equality among nursing college students, and to provide basic data for educational solutions and desirable directions. METHODS: A Q-methodology which provides a method of analyzing the subjectivity of each item was used. 34 selected Q-statements from each of 20 women nursing college students were classified into a shape of normal distribution using 9-point scale. Subjectivity on the equality among genders was analyzed by the pc-QUANL program. RESULTS: Four types of awareness of gender equality in nursing college students were identified. The name for type I was 'pursuit of androgyny', for type II, 'difference-recognition', for type III, 'human-relationship emphasis', and for type IV, 'social-system emphasis'. CONCLUSION: The results of this study indicate that different approaches to educational programs on gender equality are recommended for nursing college students based on the four types of gender equality awareness.

Exposure to Workplace Violence and Coping in Intensive Care Unit Nurses / 정신간호학회지

PURPOSE: The purpose of this study was to examine workplace violence (verbal, physical, and sexual violence) among nurses in intensive care units (ICU). METHODS: This cross-sectional survey was done from November 8 to 27, 2010, using self-administered questionnaires. The responses of 251 nurses were analyzed. RESULTS: The results of this study showed that ICU nurses frequently experience workplace violence. Verbal violence was more frequent than physical or sexual violence. The most frequent action taken by respondents after violence was seeking help from colleagues. Violence occurred most often when a patient's mental status was altered or the patient had too much alcohol, and when the patient or family was not satisfied with the hospital services because of delay of test results or treatment. In addition, miscommunication between doctors and nurses or among nurses was a major reason for violent behavior. Nurses regarded public apologies, professional counseling, and communication skill training as effective methods to prevent or deal with violence. CONCLUSION: These results suggest that institutional and administrative support to promote a safe and efficient work environment in hospitals should be provided to minimize the possibilities of violent behavior by patients or patients' families directed at medical personnel.

Effects of Postpartum Depression and Temperament of Infant on Child-care Stress among Mothers of Newborn Infants

PURPOSE: This study was designed to identify mother and infant related factors that influence child-care stress among the mother of newborn infants. METHODS: Data were collected through self-administered questionnaires and descriptive statistics, correlation and multiple regression were used to analyze the data. The data survey was conducted with 957 conveniently selected mothers of infants when they visited a public health center in Seoul to have their children immunized. RESULTS: The average item score for the Childcare Stress Inventory was 38.03, for the Edinburgh Postnatal Depression Scale, 9.31 and for the Degree of Bother Inventory, 23.42. The CSI was positively correlated to EPDS (r=.44, p<.001) and DBI (r=.40, p<.001). Also these two variables explained 30.0% of CSI in infants' mothers. CONCLUSION: These findings are expected to expand the understanding about postpartum mothers' child-care stress and can contribute to the development of comprehensive interventions based on community health nursing.

Psychological and Spiritual Factors Associated with Death Anxiety of Elderly People Living at Home / 정신간호학회지

PURPOSE: The study was done to investigate psychological spiritual factors related to death anxiety of elderly living at home. METHODS: A descriptive correlation study was conducted. The participants were 494 living at home elderly people conveniently selected in Seoul and Kyunggi province. Data were collected using self-administered questionnaires. Descriptive statistics, t-test, ANOVA, correlation and stepwise multiple regression were used for data analysis. RESULTS: The death anxiety positively correlated with depression and negatively with self-integrity, readiness of death, belief in life after death, and spiritual well-being. The factors influencing death anxiety were self-integrity, readiness of death, depression, and belief in life after death. Those four variables explained 21.6% of death anxiety. CONCLUSION: It is expected to serve as a useful tool for nurses who serve elderly people in the clinical field and local community to help get a better understanding of death, and it is expected to lay a theoretical foundation for the development of strategies geared toward alleviating death anxiety.

Psychological and Spiritual Factors Associated with Death Anxiety of Elderly People Living at Home / 정신간호학회지

PURPOSE: The study was done to investigate psychological spiritual factors related to death anxiety of elderly living at home. METHODS: A descriptive correlation study was conducted. The participants were 494 living at home elderly people conveniently selected in Seoul and Kyunggi province. Data were collected using self-administered questionnaires. Descriptive statistics, t-test, ANOVA, correlation and stepwise multiple regression were used for data analysis. RESULTS: The death anxiety positively correlated with depression and negatively with self-integrity, readiness of death, belief in life after death, and spiritual well-being. The factors influencing death anxiety were self-integrity, readiness of death, depression, and belief in life after death. Those four variables explained 21.6% of death anxiety. CONCLUSION: It is expected to serve as a useful tool for nurses who serve elderly people in the clinical field and local community to help get a better understanding of death, and it is expected to lay a theoretical foundation for the development of strategies geared toward alleviating death anxiety.

Human Studies on Functional Foods: How They Are Regulated

Along with the steady growth of health functional food (HFF) markets, research evaluating the human effects of HFF has been expanding. In this study, we investigated the regulatory and management system of human study on HFF in the USA, Japan and UK, and the Korean domestic regulations on HHF, medicines, medical devices, cosmetics and biotechnology in order to improve the domestic management system. In these four countries, institutional review board (IRB) or research ethics committee (REC) approvals are required for on human study of HHF, but regulatory and management systems differ from country to country. In the USA, human studies on HFF for structure/function claims do not require the FDA's prior approval but clinical trials of the disease treatment effects of HHF require prior approval from the FDA. In the USA, IRBs are managed by the Department of Health and Human Services (DHHS) rather than the FDA, and IRBs in those institutions which would execute the clinical trials requiring prior approval from the FDA or human studies funded by the USA federal government are required to be registered on the DHHS. In the UK, although the government does not require prior approval of human study, authorized RECs managed by the National Research Ethics Service (NRES) and other independent RECs review the human study. In Japan, human study for HFF must conform with "Ethical guidelines for epidemiological research" and IRB registration has not been required. In Korean domestic regulations, the responsibilities, compositions, functions and operations of IRBs on medicines, medical devices and biotechnology are legally specified, but not those of IRB on HHF. These foreign statuses for the management of human study on HFF and comparisons with Korean regulations are expected to be used as basic data to improve the domestic legal system.

The Relationship of Sexual Satisfaction and Daily Stress in the Breast Cancer Patients / 성인간호학회지

PURPOSE: The purpose of this study was to investigate the correlation of sexual satisfaction and daily stress in breast cancer patients. METHODS: Data was collected through self-administered questionnaires and analyzed by descriptive statistics, t-test, ANOVA and Pearson's correlation. Data survey was conducted with 500 conveniently selected breast cancer patients who visited the out patient department in 5 university hospitals in Seoul, Gyung-gi and Gang-won province. RESULTS: The sexual satisfaction of breast cancer patients score was 31.34 and there were significant sexual satisfaction differences by age, education level, menopause and sexual activity frequency. Sexual satisfaction was negatively related with daily stress (r = -.177) especially personal stress (r = -.155), economic stress (r = -.138), stress of self (r = -.181), family stress (r = -.154) and stress about leisure (r = -.139). CONCLUSION: These findings are expected to make a contribution to creation of ideal sexual rehabilitation nursing interventions for breast cancer patients care nurse. Furthermore continuous and customized education and counseling programs can contribute to promote healthy sexual life for breast cancer patients.

Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats

The aim of this study was to examine the hypoglycemic effect of chlorella in 6 week-old type 2 diabetic Goto-Kakizaki (GK, n=30) rats and 6 week-old normal Wistar (n=30) rats. Animals were randomly assigned to 3 groups respectively, and were fed three different experimental diets containing 0%, 3% or 5% (w/w) chlorella for 8 weeks. In diabetic GK rats, the insulinogenic-indices were not significantly different among the groups. The concentrations of fasting plasma glucagon and hepatic triglyceride, and the insulin/glucagon ratios of the GK-3% chlorella and GK-5% chlorella groups were significantly lower than those of the GK-control group. The HOMA-index and the concentrations of fasting blood glucose and plasma insulin of the GK-3% chlorella and GK-5% chlorella groups were slightly lower than those of the GK-control group. In normal Wistar rats, the insulinogenic-indices were not significantly different among the normal groups, but that of the Wistar-5% chlorella group was slightly higher than the other groups. The concentrations of fasting blood glucose and plasma insulin, and the HOMA-index of the Wistar-5% chlorella group were a little higher, and the fasting plasma glucagon concentration and the insulin/glucagon ratio of the Wistar-5% chlorella group were significantly higher than those of the Wistar-control and Wistar-3% chlorella groups. In conclusion, this study shows that the glucose-stimulated insulin secretion was not affected by the intake of chlorella, which could be beneficial, however, in improving insulin sensitivity in type 2 diabetic GK and normal Wistar rats.

A case of perivascular epithelioid cell tumor (PEComa) at the uterus / 대한산부인과학회지

Perivascular epithelioid cell tumors (PEComas) at the uterus are very rare tumors and about 30 cases have been reported as far as we know. As a case was experienced at our hospital, we would like to report it with a brief review of literature.

A case of right rudimentary uterus with ipsilateral renal agenesis misdiagnosed as an ovarian tumor / 대한산부인과학회지

Rudimentary uterus with ipsilateral renal agenesis is a very rare Mullerian duct malformation. The most common clinical presentation is pelvic pain and dysmenorrhea shortly after menarche, in associated with the finding of a vaginal or pelvic mass. An appropriate and prompt diagnosis and treatment will prevent unnecessary procedures and offer relief of symptoms. We report one case of rudimentary uterine horn with ipsilateral renal agenesis with a brief review of concerned literatures.

One case of primary malignant mixed Mullerian tumor of the pelvic peritoneum / 부인종양

Malignant mixed mullerian tumor (MMMT) is a tumor in which carcinoma (an epithelial malignancy) is mixed with sarcoma (a nonepithelial malignancy). Extrauterine MMMTs are extremely rare, and only 32 cases are reported according to the literature. We experienced a case of primary peritoneal MMMT and repot with a brief review of literature.

Increased expressions of claudin-1 and claudin-7 in cervical squamous intraepithelial neoplasias and invasive squamous cell carcinomas / 대한산부인과학회지

OBJECTIVE: The change of claudin expressions, integral transmembrane proteins for tight junction, might be related to progression of cervical premalignancy or malignancy. The aim of this study was to verify the tendency of expressions of claudin-1 and -7 according to the progression of cervical pathology of uterus. METHODS: There were 162 tissues obtained at AA institute. 25 tissues were normal, 26 were cervical intraepithelial neoplasia (CIN) 1, 30 were CIN2, 44 were CIN3, 25 were microinvasive cervical carcinomas, and 12 were invasive squamous cervical carcinomas (ISCC). H and E and immunohistochemical staining were done. RESULTS: Among normal tissues, 52% showed no expression, 48% weak expressions at claudin-1, and 28% no expression, 56% weak expressions at claudin-7. Among CIN3, 20% showed weak expressions, 41% showed moderate expressions at claudin-1, and 14% weak expressions, 52% moderate expressions at claudin-7. Among ISCC, 42% showed moderate expressions, 50% strong expressions at claudin-1, and 33% moderate expressions, and 33% strong expressions at claudin-7. These data shows the increasing tendency of claudin-1 and claudin-7 expressions according to the severity of lesions (p<0.01). CONCLUSION: The expressions of claudin-1 and claudin-7 were increased more according to the progression of cervical lesions.