Intraocular Pressure and Ocular Biometry Change of Healthy Eyes in Postural Variation

PURPOSE: To investigate intraocular pressure (IOP) and ocular biometry change according to the posture change in healthy eyes. METHODS: Forty eight eyes of 48 healthy young subjects were enrolled. IOP, central anterior chamber depth (cACD), and axial length were measured after keeping each position for 10 minutes (upright, sitting, supine, and prone positions) by using the TonoPen(R) and A-scan ultrasonography. RESULTS: Mean IOP was 19.68 +/- 2.15 mm Hg in prone position, 17.19 +/- 1.33 mm Hg in supine position, 16.49 +/- 1.76 mm Hg in sitting position, and 15.33 +/- 1.34 mm Hg in upright position. Difference among the positions was statistically significant (p < 0.01). Mean cACD was 3.68 +/- 0.35 mm in upright position, 3.63 +/- 0.32 mm in supine position, 3.59 +/- 0.34 mm in sitting position, and 3.47 +/- 0.30 mm in prone position. Difference among the positions was statistically significant (p < 0.01) except for the difference between supine and sitting position. Linear regression analysis revealed that cACD was significantly associated with IOP in prone position (R2 = 0.139, p < 0.01). CONCLUSIONS: There was a significant change in IOP and cACD according to the posture change. cACD was significantly associated with IOP only in prone position.

Moyamoya Disease Initially Presenting Transient Visual Loss

PURPOSE: To report a case of moyamoya disease initially presenting transient visual loss in a healthy young subject. CASE SUMMARY: A 20-year-old male with no history of systemic disease or trauma visited our clinic due to sudden onset visual loss in the right eye. There were no accompanying symptoms, including headache, seizure, paresis, or paresthesia. Best corrected visual acuity at the first visit was hand movement in the right eye and 20/20 in the left eye. No abnormal finding was revealed in the anterior segment. On fundus examination, whitening at post pole was found in the right eye. In fluorescein angiography, a choroidal and retinal artery filling delay in the posterior pole was noted. The patient's visual acuity began to improve gradually and was recovered to 20/20 by the next day. Moyamoya disease was diagnosed based on magnetic resonance angiography of the brain and transfemoral cerebral angiography as well as stenosis of the internal carotid artery and middle cerebral artery with collateral vessel networks. CONCLUSIONS: Moyamoya disease should be considered as a possible cause of transient visual loss in healthy young subjects.