ABSTRACT
Until the recent development of the Q-switched lasers, it was not possible to remove tattoos without permanent scarring and pigmentary changes. Among the Q-switched lasers which was introduced under the concept of selective photothermolysis, Q-switched Nd-YAG laser has a longer wave(1064nm), deeper penetration, and lesser pigmentary change of skin than other type Q-switched laser. So, proved effectivity in removing pigmented lesion and tattoos without scarring and pigmentary changes. But repeated treatment is essential for a good result and than there is no agreement on the treatment interval in using Q-switched Nd-YAG laser. In this experiment, the author tattooed on the back skin of rabbits and treated them twice using Q-switched Nd-YAG laser in 5 groups of different treatment interval(1,2,4,6,8 weeks). The authors analysed the histology and final therapeutic results of the 5 groups to find a reasonable and shorter treatment interval by which we can obtain an effective therapeutic result without causing permanent tissue injury and change of the skin texture. The result shows that the 4 week treatment interval of Q-switched Nd-YAG laser for the tattoo removal in rabbits is the shortest term by which we can get effective therapeutic results without permanent scar and pigmentary changes.
Subject(s)
Rabbits , Cicatrix , Lasers, Solid-State , SkinABSTRACT
Until the recent development of the Q-switched lasers, it was not possible to remove tattoos without permanent scarring and pigmentary changes. Among the Q-switched lasers which was introduced under the concept of selective photothermolysis, Q-switched Nd-YAG laser has a longer wave(1064nm), deeper penetration, and lesser pigmentary change of skin than other type Q-switched laser. So, proved effectivity in removing pigmented lesion and tattoos without scarring and pigmentary changes. But repeated treatment is essential for a good result and than there is no agreement on the treatment interval in using Q-switched Nd-YAG laser. In this experiment, the author tattooed on the back skin of rabbits and treated them twice using Q-switched Nd-YAG laser in 5 groups of different treatment interval(1,2,4,6,8 weeks). The authors analysed the histology and final therapeutic results of the 5 groups to find a reasonable and shorter treatment interval by which we can obtain an effective therapeutic result without causing permanent tissue injury and change of the skin texture. The result shows that the 4 week treatment interval of Q-switched Nd-YAG laser for the tattoo removal in rabbits is the shortest term by which we can get effective therapeutic results without permanent scar and pigmentary changes.
Subject(s)
Rabbits , Cicatrix , Lasers, Solid-State , SkinABSTRACT
The perichondrium has neochondrogenic potential. Many authors have published their study for the cartilage regeneration from perichondrium and the clinical uses of perichondrial graft. How is the difference of thickness of the regenerated cartilage after crushing the free perichondrial graft, compare with uncrushed graft? In this study, the perichondrium was obtained from rabbit, ears, and sectioned 10x10 mm slices. The uncrushed and crushed perichondriums were grafted into subcutaneous layer of back. After the 2,4 and 8 weeks, authors obtained regenerated cartilage from both crushed and uncrushed free perichondrial graft from rabbit back, examined the survival rate and thickness by histologic study.The results are as follows: 1. The survival rate was no difference between the uncrushed perichondrium & crushed perichondrium (p>0.05). 2. The cartilage from the uncrushed perichondrium was thicker than the crushed perichondrium, at only 8 weeks(p0.05).
Subject(s)
Humans , Cartilage , Ear , Regeneration , Survival Rate , Tissue Donors , TransplantsABSTRACT
A retrospective, multivariate statistical analysis of 394 patients who underwent cleft palate repair was performed to document the incidence of postoperative oronasal fistula formation, and to assess possible contributing factors. Fistulas of the secondary palate were included, but nasal-alveolar fistulas and intentionally unrepaired anterior palatal fistulas were excluded. Postoperative oronasal fistulas occurred in 25 of the 394 patients(6.35%). The mean age at repair was 16.4 months, and mean follow-up period was 2.5 years. Several variables that are included sex, age, extent of clefting(as estimated by the Veau classification), type of repair, and experience level of the operating surgeon were analyzed by means of the log-rank test to determine their significance in postoperative fistula formation. Sex (p=0.077), age(p=0.538), and experience level of the operating surgeon(p=0.094) did not significantly affect the rate of fistula formation. However, extent of clefting(p=0.005) and type of repair(p=0.001) are the strongest predictor of the occurrence of a cleft palate fistula.
Subject(s)
Humans , Cleft Palate , Fistula , Follow-Up Studies , Incidence , Intention , Palate , Retrospective StudiesABSTRACT
Extraskeletal bone-forming lesions are myositis ossificans, fibrodysplasia(myositis) ossificans progressiva, and extraskeletal osteosarcoma. It is of paramount importance to clearly distinguish these lesion from extraskeketal osteosarcoma. Myositis ossificans, by far the most common among these lesions, is a benign, ossifying process that is generally solitary and well circumscribed. It is found most commonly in the musculature, but it may also occur in other tissue, especially in tendons and subcutaneous fat. It occur as the result of various kinds of soft tissue injury(surgical scars, burns, dislocation of joints etc.) and also observed in patients with tetanus, in paraplegics secondary to traumatic spinal injury. Although there is general agreement that myositis ossificans is a nonprogressive benign process without nerplastic potential, its pathogenesis is still poorly understood.We experienced a myositis ossificans associated with chronic, extensive pressure sore in patient with paraplegia secondary to spinal injury.