ABSTRACT
BACKGROUND: Supernumerary nostril is a congenital anomaly that contains additional nostril with or without accessory cartilage. These rare congenital nasal deformities result from embryological defects. Since 1906, Lindsay (Trans Pathol Soc Lond. 57:329–330, 1906) has published the first research of bilateral supernumerary nostrils, and only 34 cases have been reported so far in the English literature. CASE PRESENTATION: A 1-year-old female baby was brought to our department group for the treatment of an accessory opening above the left nostril which had been presented since her birth. Medical history was non-specific and her birth was normal. The size of a supernumerary nostril was about 0.2 cm diameter and connected to the left nostril. The right one was normal. Minimal procedure was operated for the anomaly. After 1 year, rhinoplasty was performed for the nostril asymmetry. CONCLUSIONS: At 1 year follow-up, the functional and cosmetic result was satisfactory. In this case, it is important that we have early preoperative diagnosis. Also, it is desirable that we should perform a corrective surgery as soon as possible for the patient's psychosocial growth.
Subject(s)
Female , Humans , Cartilage , Congenital Abnormalities , Diagnosis , Follow-Up Studies , Parturition , RhinoplastyABSTRACT
Subject(s)
Humans , Infant , Male , Cleft Lip , Cleft Palate , Mouth , Mouth Floor , Palate , Palate, Soft , UvulaABSTRACT
Subject(s)
Adult , Female , Humans , Hemangioma , Mouth , Mouth Floor , Neurilemmoma , Peripheral Nerves , Schwann Cells , TongueABSTRACT
Subject(s)
Humans , Biopsy , Carcinoma, Squamous Cell , Dentigerous Cyst , Epithelium , Follow-Up Studies , Jaw , Mandible , Mouth Mucosa , Odontogenic Cysts , RecurrenceABSTRACT
OBJECTIVE: A national survey was conducted to assess orthodontic residents' current concepts and knowledge of cleft lip and palate (CLP) management in Korea. METHODS: A questionnaire consisting of 7 categories and 36 question items was distributed to 16 senior chief residents of orthodontic department at 11 dental university hospitals and 5 medical university hospitals in Korea. All respondents completed the questionnaires and returned them. RESULTS: All of the respondents reported that they belonged to an interdisciplinary team. Nineteen percent indicated that they use presurgical infant orthopedic (PSIO) appliances. The percentage of respondents who reported they were 'unsure' about the methods about for cleft repair operation method was relatively high. Eighty-six percent reported that the orthodontic treatment was started at the deciduous or mixed dentition. Various answers were given regarding the amount of maxillary expansion for alveolar bone graft and the estimates of spontaneous or forced eruption of the upper canine. Sixty-seven percent reported use of a rapid maxillary expansion appliance as an anchorage device for maxillary protraction with a facemask. There was consensus among respondents regarding daily wearing time, duration of treatment, and amount of orthopedic force. Various estimates were given for the relapse percentage after maxillary advancement distraction osteogenesis (MADO). Most respondents did not have sufficient experience with MADO. CONCLUSIONS: These findings suggest that education about the concepts and methods of PSIO and surgical repair, consensus regarding orthodontic management protocols, and additional MADO experience are needed in order to improve the quality of CLP management in Korean orthodontic residents.
Subject(s)
Humans , Infant , Cleft Lip , Consensus , Surveys and Questionnaires , Dentition, Mixed , Hospitals, University , Korea , Orthodontic Extrusion , Orthopedics , Osteogenesis, Distraction , Palatal Expansion Technique , Palate , Surveys and Questionnaires , Recurrence , TransplantsABSTRACT
Subject(s)
Ethanolamine , Head , Hemangioma , Laser Therapy , Neck , Oleic Acid , Oleic Acids , Sclerotherapy , Vascular MalformationsABSTRACT
Subject(s)
Humans , Acetic Acid , Chloroform , Ethanol , Odontogenic Cysts , Odontogenic Tumors , Recurrence , World Health OrganizationABSTRACT
INTRODUCTION: The enlargement and deformation of the orbit give rise to a visible enophthalmos. As a consequence, a disturbance of eye motility together with double images is likely to occur. This study examined the degree of enophthalmos according to the extent of orbital wall fracture and volume of herniated orbital tissue in blowout fractures of the medial and inferior orbital wall. MATERIALS AND METHODS: This study was performed on patients diagnosed with medial and inferior orbital wall fractures at the Department of Oral and maxillofacial surgery, Chonbuk National University Hospital from 2007 to 2009. The patients' age, gender, etiology of fracture and degree of enophthalmos were investigated. The changes in the degree of enophthalomos, diplopia and ocular motility restriction after operation were examined. RESULTS: The degree of enophthalomos increased with increasing extent of orbital wall fracture and volume of herniated orbital tissue. CONCLUSION: Whether to perform the operation is decided after measuring the extent of the orbital wall fracture and volume of herniated orbital tissue using computed tomography (CT), time for the decision of operation can be shortened. This can cause a decrease in the complications of orbital wall fractures.
Subject(s)
Humans , Diplopia , Enophthalmos , Eye , Orbit , Surgery, OralABSTRACT
Subject(s)
Humans , Cleft Lip , Congenital Abnormalities , Jaw Abnormalities , Malocclusion , Nose , Palate , Rhinoplasty , SuccinatesABSTRACT
Subject(s)
Humans , Malocclusion , Mandible , Osteotomy, Sagittal Split Ramus , Prognathism , Recurrence , Retrospective StudiesABSTRACT
Subject(s)
Humans , Electromyography , Facial Nerve , Facial Paralysis , Follow-Up Studies , Neural Conduction , Orthognathic Surgery , Osteotomy, Sagittal Split Ramus , Paralysis , PrognathismABSTRACT
INTRODUCTION: Heat shock protein70 (HSP70) is a highly conserved family of proteins produced after a variety of stresses. Many studies reported that the overexpression of HSP70 can improve the prognosis of the patients with sepsis through a reduction of the nitric oxide concentration. However, these results only revealed the effect of HSP70 and nitric oxide. No studies have examined the relationship between HSP70 and nitric oxide. The aim of this study was to evaluate the effect of the overexpression of HSP70 on the expression of inducible nitric oxide synthase and the nitric oxide concentration. In addition, the mechanism of the relationship of HSP70 and inducible nitric oxide synthase (iNOS) in sepsis was examined. MATERIALS AND METHODS: The experiments were performed on male sprague-dawley rats. Sepsis was induced by a cecal ligation and puncture (CLP). Glutamine (GLN) or saline was administered 1 hour after the initiation of sepsis. Serum and lung tissues were acquired from the rats 12 hours or 24 hours after the initiation of sepsis. The nitric oxide concentration, the expression of HSP70 in lung, and the gene expression of iNOS in lung were analyzed. The three groups, sham operation, CLP and CLP+GLN, were compared. RESULTS: Compared to the other groups, in CLP+GLN, GLN administered after the initiation of sepsis enhanced the expression of HSP70 in the lung at 12 hours (47.19+/-10.04 vs. 33.22+/-8.28, P=0.025) and 24 hours (47.06+/-10.60 vs. 31.90+/-4.83, P=0.004). In CLP+GLN, GLN attenuated the expression of iNOS messenger RNA (mRNA) in the lung at 12 hours (5,513.73+/-1,051.60 vs. 4,167.17+/-951.59, P=0.025) and 24 hours (18,740.27 +/-8,241.20 vs. 9,437.65+/-2,521.07, P=0.016), and reduced the concentration of nitric oxide in the serum at 12 hours (0.86+/-0.48 vs. 3.82+/-2.53, P=0.016) and 24 hours (0.39+/-0.25 vs. 1.85+/-1.70, P=0.025). CONCLUSION: The overexpression of HSP70 induced by the administration of GLN in sepsis attenuates the expression of the iNOS gene but reduces the nitric oxide concentration.
Subject(s)
Animals , Humans , Male , Rats , Gene Expression , Glutamine , Heat-Shock Proteins , Hot Temperature , HSP70 Heat-Shock Proteins , Ligation , Lung , Nitric Oxide , Nitric Oxide Synthase , Nitric Oxide Synthase Type II , Prognosis , Proteins , Punctures , Rats, Sprague-Dawley , RNA, Messenger , Salicylamides , Sepsis , ShockABSTRACT
Subject(s)
Humans , Cicatrix , Follow-Up Studies , Genioplasty , Incidence , Intention , Mandible , Mandibular Nerve , Mouth , Nerve Fibers , Neural Conduction , Osteotomy , Osteotomy, Sagittal Split Ramus , Prognathism , RetrognathiaABSTRACT
Subject(s)
Humans , Bone Transplantation , Malocclusion , Osteotomy , Recurrence , Retrospective StudiesABSTRACT
Subject(s)
Female , Humans , Male , Bicuspid , Mandible , Molar , Salivary Glands , Submandibular Gland , ToothABSTRACT
Likely to be the most common oral cancer, squamous cell carcinoma(SCC) of the tongue accounts for about 20% of all oral and pharyngeal cancers. SCC of the tongue frequently arises in the lateral border, and if it metastasize, it occurs on submandibular gland and neck lymph nodes. Location of the primary lesions and neck lymph node metastasis affect the prognosis and decrease survival rate of patients with carcinoma of the tongue. The authors experienced the patient with contralateral neck lymph node metastasis of SCC of the tongue. The patient came to our department with chief complaint of elevated lesion on left lateral border of the tongue. The mass was diagnosed as T2N0M0, Stage II invasive SCC of oral tongue. Computed tomography(CT) & magnetic resonance imaging(MRI) which were taken before the operation showed no significant finding of metastasis. Surgical mass removal and preventive neck dissection on the left side were done. While follow up PET/CT, contralateral neck lymph node metastasis(right side, level II) was detected, and re-operation(Rt. side RND) was done. There are few studies concerning the contralateral neck lymph node metastasis related with SCC of the tongue. The purpose of this report is to introduce the uncommon case of contralateral neck lymph node metastasis occurred in the T2-stage of SCC of the tongue treated by surgical resection.
Subject(s)
Humans , Carcinoma, Squamous Cell , Follow-Up Studies , Lymph Nodes , Magnetic Resonance Spectroscopy , Mouth Neoplasms , Neck , Neck Dissection , Neoplasm Metastasis , Pharyngeal Neoplasms , Porphyrins , Prognosis , Submandibular Gland , Survival Rate , Tongue , Tongue NeoplasmsABSTRACT
PURPOSE: The aim of this study is to analyze the correlation between incidence of mandibular angle fracture and eruption state of mandibular third molar using clinical and radiographic findings. MATERIALS AND METHODS: The data were obtained from the clinical and radiographic records of 205 patients who visited the Department of Oral and Maxillofacial Surgery, Chonbuk National University Hospital for treatment of the mandibular fracture. Panoramic radiographies were taken for radiographic examination and the mandibular third molars were classified according to age, gender, position and eruption state. Data were analyzed by a chi-square statistics. RESULTS: In this study, the incidence of mandibular angle fracture had a tendency to be greater when a mandibular third molar was present(p>0.05), but there was not a statistically significant difference. Of the 255 cases with a mandibular third molar, 67 had an angle fractures. Of the 155 cases without a mandibular third molar, 138 had not angle fracture. And the incidence of mandibular angle fracture was high at class BII(by Pell & Gregory system) (p<0.05). CONCLUSION: Although there was not a statistically significant difference, mandibular third molar was more susceptible to mandibular angle fracture. When the reduction of mandibular angle fracture, it was recommended that mandibular third molar should be extracted especially in case of pericoronitis, periodontitis and other infections.
Subject(s)
Humans , Incidence , Mandibular Fractures , Molar, Third , Pericoronitis , Periodontitis , Radiography, Panoramic , Surgery, OralABSTRACT
PURPOSE: The aim of this study was to evaluate the effect of overexpression of heat shock protein 70 (HSP70) on the expression of inducible nitric oxide synthase and on the concentration of nitric oxide and to determine the mechanism for the relationship between HSP70 and inducible nitric oxide synthase (iNOS) in sepsis. METHODS: Experiments were performed on male Sprague-Dawley rats, and sepsis was induced by using cecal ligation and puncture (CLP). Glutamine (GLN) or saline was administered 1 h after initiation of sepsis. We acquired serum and lung tissues from the rats 12 h or 24 h after initiation of sepsis. We analyzed the concentration of nitric oxide, the expression of HSP70 in the lung, and the gene expression of iNOS in the lung. RESULTS: In CLP+GLN, glutamine given after initiation of sepsis enhanced the expression of HSP70 in the lung at 12 h (CLP+GLN vs. CLP:: 47.19 +/- 10.04 vs. 33.22 +/- 8.28, p = 0.025) and 24 h (CLP+GLN vs. CLP: 47.06 +/- 10.60 vs. 31.90 +/- 4.83, p = 0.004). In CLP+GLN, glutamine attenuated the expression of iNOS mRNA in the lung at 12 h (CLP+GLN vs. CLP: 4167.17 +/- 951.59 vs. 5513.73 +/- 1051.60, p = 0.025) and 24 h (CLP+GLN vs. CLP: 9,437.65 +/- 2,521.07 vs. 18,740.27 +/- 8,241.20, p = 0.016) and reduced the concentration of nitric oxide in serum at 12 h (CLP+GLN vs. CLP: 0.86 +/- 0.48 vs. 3.82 +/- 2.53 micromol/L, p = 0.016) and 24 h (CLP+GLN vs. CLP: 0.39 +/- 0.25 vs. 1.85 +/- 1.70 micromol/L, p = 0.025). CONCLUSION: The overexpression of HSP70 induced by the administration of glutamine in sepsis attenuated the gene expression of iNOS and reduced the concentration of nitric oxide.
Subject(s)
Animals , Humans , Male , Rats , Gene Expression , Glutamine , Heat-Shock Proteins , Hot Temperature , HSP70 Heat-Shock Proteins , Ligation , Lung , Nitric Oxide , Nitric Oxide Synthase , Nitric Oxide Synthase Type II , Punctures , Rats, Sprague-Dawley , RNA, Messenger , SepsisABSTRACT