ABSTRACT
Skull base osteomyelitis (SBO) is a rare disease and may develop as a complication of paranasal sinusitis or other regional infectious process. The characteristic symptom of SBO is headache and paralysis of cranial nerve. A potentially life-threatening disease, it requires aggressive antibiotic treatment. We present 2 cases of SBO. One case who were not immunocompromised or diabetics had paralysis of lower cranial nerves. The patient was effectively treated with complete mastoidectomy and antibiotics, so had a complete recovery. But, the other patient who were insulin-dependent diabetes mellitus was died due to meningitis and pons palsy.
Subject(s)
Aged , Humans , Anti-Bacterial Agents , Cranial Nerve Diseases , Cranial Nerves , Diabetes Mellitus, Type 1 , Headache , Meningitis , Osteomyelitis , Paralysis , Pons , Rare Diseases , Sinusitis , Skull , Skull BaseABSTRACT
Osteosarcoma is a highly malignant bone tumor that is rarely found in the facial and cranial bones. It may be found in the mandible and maxilla but is very rare in the temporal bone. Surgery with adequate margins seems to be the procedure of choice and postoperative chemotherapy and radiotherapy is recommended as well as a long term follow up. The authors experienced a case of osteosarcoma of the temporal bone in a 39 years-old male. The patient underwent a tumor removal with open craniotomy and simple mastoidectomy; then, the mastoid was obliterated by temporalis muscle rotation flap. After operation, the patient received chemotherapy. The patient has been free of local recurrence or metastasis for 2 postoperative years.
Subject(s)
Adult , Humans , Male , Craniotomy , Drug Therapy , Follow-Up Studies , Mandible , Mastoid , Maxilla , Neoplasm Metastasis , Osteosarcoma , Radiotherapy , Recurrence , Temporal BoneABSTRACT
Syphilis was a common cause of progressive or sudden sensorineural hearing loss. After introduction of penicillin, the incidence of syphilis decreased in general population. However, with the prevalence of HIV infection, it's incidence is increasing. Many studies have substantiated the aggressive and rapidly progressive behavior of neurosyphilis, including otosyphilis, in the presence of HIV infection . We report a case of 38-year-old man HIV infected patient with bilateral sensorineural hearing loss and bilateral total vestibular loss caused by otosyphilis which was resistant to treatment.