[ relationship between women physical fitness and obesity and the severity of CAD]

Ischemic heart disease is the most prevalent cause of mortality in women and change in lifestyle including better physical fitness could control this condition. To determine the relationship between physical fitness and obesity in women with coronary involvement. In this cross-sectional study, 113 women aged 40-60 with stable angina, were included. Demographic details and past medical history [hypertension, diabetes, and hyperlipidemia] were collected using a questionnaire. Also, the Duke Activity Scale questionnaire [including 12 questions] was completed for each patient. Later, a coronary angiography using Seldinger method was performed and the extent score determined. The body mass index was also calculated. Data were evaluated using SPSS/12, t-student test, and the correlation and regression analysis. The mean age, coronary involvement score, and the Duke Score were 50.18 +/- 8.71 years, 5.85 +/- 5.50 and 22.35 +/- 14.75, respectively. The coronary involvement score in women with diabetes, hyperlipidemia, and hypertension was higher than those without such complications [p<0/05]. However, the activity scale was shown to have insignificant difference. In addition, there were significant differences between the scale of physical fitness and both the coronary score and the body mass index [P<0.0001, r=-0.33] and [P<0.02, r=-0.21], respectively. Nevertheless, no relationship between the obesity and coronary involvement was demonstrated [P>0.05]. According to our data, we must have more attention on physical fitness in women beside other change in life style

[Relationship between hematological factors and metabolic syndrome in an iranian population isfahan healthy heart program]

Metabolic syndrome is considered as one of the risk factor for Cardio Vascular Disease [CVD]. Correlation between this syndrom and white and red blood cell counts is unknown whereas the relationship between insulin resistance and hamatologic factors is indicated in some published articles. The purpose of this study was to assess the correlation between hematologic parameters and metabolic syndrome. In a descriptive study 11974 over 19 years old participants in Isfahan, Najaf-Abad and Arak in rural and urban areas was evaluated as part of Isfahan Healthy Heart Program [IHHP] study . At first these participants' demographic data [age, sex, past history and drug consumption] were collected then trained physicians measured their blood pressure and waist circumference. Blood pressure in two separate occasions was recorded and mean of these measures was used in this study. In all participants, laboratory examinations [RBC, WBC, HDL-C, FBS, TG] were done after a 12 hour fasting. Participants were evaluated for metabolic syndrome according to ATP-III criteria. Data were entered in to SPSS-11 and analyzed by t-test and Spearmen correlation. Overall 6132[51%] females and 5842[49%] males with mean age of 35.6 +/- 3.8 and 35.9 +/- 32 year were studied respectively. The prevalence of metabolic syndrome in male and female participants were 10.6% and 35% respectively and 23/1% in overall. WBC and RBC counts were higher in patients with metabolic syndrome compared to those of normal subjects. Correlation between metabolic syndrome and RBC and WBC counts was significant excluding the case of hypertension. The most powerful correlation was obsereved between count RBC and HDL-C [r: -0.245, p<0.001], WBC and TG [r: 0.195, p<0.001]. We observed increased RBC and WBC counts in patients with metabolic syndrome. In this regard a widespread study may help us use these hematologic parameters even in normal values as indicators for evaluation of high risk patients

Obesity and its association with other cardiovascular risk factors in women's in central Iran - women healthy heart project

Cardiovascular diseases [CVD] are considered the most important cause of death worldwide. Obesity is a major CVD risk factor. This study was conducted to evaluate the prevalence of obesity and its association with other CVD risk factors in Iranian women. This cross-sectional study was conducted in 2001 as part of Isfahan Healthy Heart Program [IHHP] in three Central Iranian cities of Isfahan, Najaf-Abad and Arak. Being over 19 years of age, absence of pregnancy, absence of mental retardation and Iranian nationality were the criteria for inclusion in the study. A questionnaire on demographics characteristics, drug consumption, smoking status, and physical activity were filled out for every subject. Height, weight and blood pressure of all subjects were measured and fasting blood samples were taken to measure blood glucose and lipids. The data were analyzed with T-test, X[2] and multiple linear regression, using SPSS11. Of 6391 women aged 38.8 +/- 14.5 years participating in the study, 79% lived in the urban areas and 21% in the rural areas. The prevalence of a higher BMI was greater in urban areas in all ages. Hypertension, diabetes, total cholesterol-triglyceride and LDL-C disorders and inadequate physical activity were more prevalent in obese women than normal ones, but no significant difference was seen in HDL-C disorder and smoking between the two groups [P<0.05]. There was a significant positive relationship between BMI and age, blood glucose and urban residence, and a negative relationship was observed between BMI and inadequate physical activity [P<0.05]. The high prevalence of obesity and the major risk factors of cardiovascular diseases in urban areas is testament to unhealthy lifestyle and insufficient physical activity of women in areas studied