[Effects of electromagnetic fields on seminal vesicle in rat]

In industrial world, almost everyone is unavoidably exposed to ambient electromagnetic fields [EMF] generated from various technical and household appliances. One of the critical issues is the possibility of adverse effect of EMF on male reproductive system including the testes and accessory glands. To examine weather the EMF can adversely affect the seminal vesicle tissue. This was an experimental study in which two groups [case and control] of 15 members were investigated. The members of case group were exposed to 50 Hz non-ionizing radiation during the postnatal life for 2 months. The control group was kept in a similar situation but without exposure to EMF. Microscopic observations demonstrated that the smooth muscle fibers in capsule of tubulosecular glands were spread out in different layers and directions. Their nuclei showed signs of heterochromatinism. The number of heterochromatinized epithelial cells per microscopic field was 1.127 +/- 0.46 for the case group while it was 0.60 +/- 0.74 for the control group [p<0.01]. Epithelial secretary cells also showed cell damages. Our findings suggest that EMF exposure may cause profound changes on seminal vesicle. Therefore, exposure to EMF may result in pathological changes leading to subfertility and infertility

[Survey the effects of ciprofloxacin on rat testis tissue considering electron microscopy]

Introduction: Ciprofloxacin is a synthetic antibacterial agent belonging to the family of Fluoroquinolones with a very broad spectrum against of microbial pathogens, especially Gram-negative infectious diseases, that has been approved in more than 100 countries world-wide

Objective: The aim of this study was planed to see determine the histopathological effects of ciprofloxacin after inducement, in rat testis

Materials and Methods: The twenty male wistar rats were selected and randomly divided into two groups control [n=10] and test [n=10]. The test group was received 12.5mg/kg [PO] ciprofloxacin daily for sixty day however the control group just received plate. In sixtieth day the testis tissue of rats in both groups were removed and prepared for electron microscopy

Results: Electron microscopic studies of testis tissue slices of test group showed many changes such as: nuclei of spermatocyt I and sertoli cells and myoid were hyperchromatined. The Mitochondria of spermatogonia and spermatocyts cells in test group were vacuolated when as compared with control group. Thickness of spermatid tail in test group was increased when as compared with control group

Conclusion: There was a marked decrease in fertility index, testicular weight in experimental group as compared with control group. Since in our study ciprofloxacin had side effects on testis tissue in rat. It was suggested that using ciprofloxacin can decreasing fertility rate in human